Description
IUPAC Name: 5-hydroxy-2-methylnaphthalene-1,4-dione
InChI: InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3
InChIKey: VCMMXZQDRFWYSE-UHFFFAOYSA-N
Canonical SMILES: CC1=CC(=O)C2=C(C1=O)C=CC=C2O
Isomeric SMILES: CC1=CC(=O)C2=C(C1=O)C=CC=C2O
Synonyms: Plumbagin; 481-42-5; 5-hydroxy-2-methylnaphthalene-1,4-dione; 5-Hydroxy-2-methyl-1,4-naphthoquinone; Plumbagine; 2-Methyljuglone; Plumbaein; Plumbagone; …
Botanical Source:
Product Overview
High-purity Plumbagin, a naturally occurring naphthoquinone isolated from Plumbago species, is manufactured to exceptional standards for pharmaceutical research and anticancer studies.
Technical Specifications
- Molecular Formula: C₁₁H₈O₃
- Molecular Weight: 188.18 g/mol
- Purity: ≥98% (HPLC)
- Appearance: Yellow crystalline powder
- Solubility: Soluble in DMSO, methanol, ethanol; slightly soluble in water
Key Features & Benefits
- Natural quinone compound
- Superior biological activity
- Validated structure and purity
- Comprehensive Certificate of Analysis
- Full spectroscopic characterization
Research Applications
-
Cancer Research
- Antiproliferative studies
- Apoptosis induction research
- Cell cycle regulation
- Cancer cell resistance studies
-
Pharmaceutical Development
- Anti-inflammatory research
- Antimicrobial studies
- ROS modulation research
- Drug discovery screening
-
Mechanism Studies
- Cell signaling pathways
- Molecular target identification
- Oxidative stress research
- Enzyme inhibition studies
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Research Support
BIORLAB provides:
- Technical consultation
- Method development support
- Stability data
- Custom synthesis options
- Regulatory documentation
Key Research Areas
-
Anticancer Mechanisms
- Cell death pathways
- Cancer cell metabolism
- Drug resistance studies
- Combination therapy research
-
Antimicrobial Activity
- Bacterial growth inhibition
- Antimicrobial resistance
- Structure-activity relationships
-
Cellular Responses
- Oxidative stress
- Mitochondrial function
- Cell survival pathways
This premium-grade Plumbagin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.
For research and development purposes only. Not for human consumption or clinical use.