Plumbagin

SKU 481-42-5 Category

$35.00

CAS No.: 481-42-5
Molecular Formula C₁₁H₈O₃
Molecular Weight 188.18g/mol
Purity HPLC>98%
Chemical Family Quinones

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: 5-hydroxy-2-methylnaphthalene-1,4-dione

InChI: InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

InChIKey: VCMMXZQDRFWYSE-UHFFFAOYSA-N

Canonical SMILES: CC1=CC(=O)C2=C(C1=O)C=CC=C2O

Isomeric SMILES: CC1=CC(=O)C2=C(C1=O)C=CC=C2O

Synonyms: Plumbagin; 481-42-5; 5-hydroxy-2-methylnaphthalene-1,4-dione; 5-Hydroxy-2-methyl-1,4-naphthoquinone; Plumbagine; 2-Methyljuglone; Plumbaein; Plumbagone; …

Botanical Source:


Product Overview

High-purity Plumbagin, a naturally occurring naphthoquinone isolated from Plumbago species, is manufactured to exceptional standards for pharmaceutical research and anticancer studies.

Technical Specifications

  • Molecular Formula: C₁₁H₈O₃
  • Molecular Weight: 188.18 g/mol
  • Purity: ≥98% (HPLC)
  • Appearance: Yellow crystalline powder
  • Solubility: Soluble in DMSO, methanol, ethanol; slightly soluble in water

Key Features & Benefits

  • Natural quinone compound
  • Superior biological activity
  • Validated structure and purity
  • Comprehensive Certificate of Analysis
  • Full spectroscopic characterization

Research Applications

  1. Cancer Research

    • Antiproliferative studies
    • Apoptosis induction research
    • Cell cycle regulation
    • Cancer cell resistance studies
  2. Pharmaceutical Development

    • Anti-inflammatory research
    • Antimicrobial studies
    • ROS modulation research
    • Drug discovery screening
  3. Mechanism Studies

    • Cell signaling pathways
    • Molecular target identification
    • Oxidative stress research
    • Enzyme inhibition studies

Storage & Handling

  • Store at -20°C
  • Protect from light
  • Avoid repeated freeze-thaw cycles
  • Stock solution guidelines provided
  • 24-month stability under recommended conditions

Quality Assurance

  • GMP-compliant manufacturing
  • Rigorous quality control
  • Complete analytical documentation
  • Traceable lot numbers
  • Stability monitoring program

Research Support

BIORLAB provides:

  • Technical consultation
  • Method development support
  • Stability data
  • Custom synthesis options
  • Regulatory documentation

Key Research Areas

  1. Anticancer Mechanisms

    • Cell death pathways
    • Cancer cell metabolism
    • Drug resistance studies
    • Combination therapy research
  2. Antimicrobial Activity

    • Bacterial growth inhibition
    • Antimicrobial resistance
    • Structure-activity relationships
  3. Cellular Responses

    • Oxidative stress
    • Mitochondrial function
    • Cell survival pathways

This premium-grade Plumbagin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

Additional information

Weight

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

Testimonials

What Our Client Say

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Carol C Medical Research

Their high-quality natural products have significantly advanced our research, providing us with reliable and consistent results. BIORLAB's commitment to excellence ensures we can push the boundaries of our studies with confidence.

Chester Glass Medical Research

BIORLAB's solutions in pharmaceutical products are unparalleled. Their innovative approaches and top-notch compounds have revolutionized our development processes, making them an indispensable partner in our pursuit of groundbreaking discoveries.

Julian K Medical Research

The natural compounds from BIORLAB are always pure and effective, ensuring the highest standards in our research. Their dedication to quality and consistency sets them apart, making them our go-to source for natural pharmaceutical ingredients.

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