Description

IUPAC Name: 4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid

InChI: InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1

InChIKey: FIHJKUPKCHIPAT-AHIGJZGOSA-N

Canonical SMILES: CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C

Isomeric SMILES: C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C

Synonyms: Artesunate; Artesunic acid; Arsumax; 88495-63-0; Plasmotrin; Qinghaozhi; Saphnate; Artesunatum; …

Botanical Source: Artemisia annua L.

Artesunate, a semi-synthetic derivative of artemisinin, is provided by BIORLAB at pharmaceutical-grade purity (≥98%). This versatile compound has gained significant research interest beyond its antimalarial properties, showing promise in multiple therapeutic areas.

Technical Specifications

• Molecular Formula: C₁₉H₂₈O₈
• Molecular Weight: 384.4 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO, ethanol; sparingly soluble in water
• Purity: ≥98% (HPLC)
• Storage Temperature: -20°C

Key Research Applications

• Antimalarial Research

  • Plasmodium studies
  • Drug resistance investigation
  • Combination therapy research

• Cancer Research

  • Angiogenesis inhibition studies
  • Cell proliferation research
  • Apoptosis pathway investigation

• Anti-inflammatory Studies

  • Immunomodulation research
  • Inflammatory pathway studies
  • Cytokine regulation

Storage & Handling

• Store at -20°C under inert gas
• Protect from light and moisture
• Available in research quantities
• Reconstituted solutions stable for 24 hours at 2-8°C

Research Significance

1. Multiple Pharmacological Effects

   • Anti-parasitic mechanisms
   • Anti-tumor properties
   • Immunomodulatory activities

2. Novel Applications

   • Endometriosis treatment research
   • Angiogenesis inhibition
   • HIF-1α/VEGF pathway modulation

3. Therapeutic Development

   • Drug delivery systems
   • Novel formulations
   • Targeted therapy research

Quality Assurance

• Complete analytical documentation
• Comprehensive Certificate of Analysis
• Batch-specific purity data
• Research-grade validation

Research Focus Areas

• Parasitology

  • Malaria research
  • Drug resistance studies
  • Combination strategies

• Oncology

  • Tumor inhibition
  • Vascular targeting
  • Cell death mechanisms

Technical Support Features

• Method development assistance
• Analytical testing guidance
• Stability data available
• Research protocol support

Application Areas

1. Pharmaceutical Research

   • Drug development
   • Formulation studies
   • Bioavailability research

2. Clinical Studies

   • Reference standards
   • Method validation
   • Analytical testing

Safety & Regulatory Information

• Research use only
• Comprehensive safety data
• Handling guidelines provided
• Special storage requirements

Additional Features

• Batch-to-batch consistency
• Method validation support
• Custom packaging options
• Technical consultation
• Research collaboration potential

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.

Note: This product is intended for laboratory research purposes only. Not for human consumption or therapeutic use without proper approval.