Description

IUPAC Name: (1S,2R,6S,7R,9R,11S,12S,15R,16S)-6-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadec-4-en-3-one

InChI: InChI=1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3/t15-,16-,18+,19-,20-,21+,23-,24+,26+,27-,28+/m0/s1

InChIKey: DBRXOUCRJQVYJQ-CKNDUULBSA-N

Canonical SMILES: CC1=C(C(=O)OC(C1)C(C)C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)CO

Isomeric SMILES: CC1=C(C(=O)O[C@H](C1)[C@@H](C)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3C[C@@H]5[C@]6([C@@]4(C(=O)C=C[C@@H]6O)C)O5)C)CO

Synonyms: Withaferin A; 5119-48-2; Withaferine A; NSC 273757; WITHAFERIN DERIV JPR, IOWA U. COMPOUND; CHEBI:69120; NSC-101088; NSC101088; …

Botanical Source:

Product Overview

BIORLAB provides high-purity Withaferin A, a bioactive steroidal lactone isolated from Withania somnifera with significant applications in anticancer, anti-inflammatory, and adaptogenic research.

Technical Specifications

• Molecular Formula: C₂₈H₃₈O₆
• Source: Withania somnifera
• Appearance: White crystalline powder
• Purity: ≥98% (HPLC)
• Storage: -20°C, protected from light

Research Applications

Primary Research Areas

• Cancer research
• Anti-inflammatory studies
• Stress response research
• Immunomodulation studies

Key Research Properties

1. Biological Activities

   • Anticancer effects
   • Anti-inflammatory action
   • Heat shock response
   • Angiogenesis inhibition

2. Molecular Targets

   • NF-κB pathway
   • Vimentin
   • Heat shock proteins
   • Proteasome system

Research Significance

1. Cancer Research

   • Apoptosis induction
   • Cell cycle arrest
   • Metastasis inhibition
   • Multiple pathway targeting

2. Molecular Mechanisms

   • HSP90 inhibition
   • Cytoskeletal disruption
   • Inflammatory modulation
   • Oxidative stress response

Storage & Handling

• Store at -20°C
• Protect from light
• Available in research quantities
• Stability data provided

Quality Assurance

• Full spectroscopic characterization
• Comprehensive Certificate of Analysis
• Batch-specific HPLC profiles
• Research-grade documentation

Target Applications

• Cancer research centers
• Drug development facilities
• Academic institutions
• Pharmaceutical R&D

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.

Note: This product is intended for laboratory research purposes only.