Description
IUPAC Name: methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
InChI: InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1
InChIKey: RXPRRQLKFXBCSJ-GIVPXCGWSA-N
Canonical SMILES: CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)(C(=O)OC)O
Isomeric SMILES: CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O
Synonyms: vincamine; 1617-90-9; Pervincamine; Devincan; Angiopac; Arteriovinca; Minorine; Vincamidol; …
Botanical Source: Catharanthus roseus (L.)G. Don
Product Overview
BIORLAB presents high-purity Vincamine, a natural alkaloid with significant applications in cerebrovascular research, particularly noted for its protective effects against hepatic fibrosis and inflammatory conditions.
Technical Specifications
- Source: Vinca minor L.
- Category: Indole alkaloid
- Purity: ≥98% (HPLC)
- Storage: -20°C, protected from light
Key Research Applications
Primary Research Areas
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Hepatic Research
- Hepatic fibrosis inhibition
- S100A4-mediated pathways
- FXR activation regulation
- Liver microenvironment studies
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Anti-inflammatory Studies
- Corneal epithelial protection
- LPS-induced inflammation reduction
- Oxidative stress modulation
- Thioredoxin reductase activation
Research Significance
Biological Activities
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Hepatoprotective Effects
- ECM deposition regulation
- Inflammatory factor modulation
- FXR/TGR5 pathway regulation
- Intestinal barrier protection
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Molecular Mechanisms
- S100A4 inhibition
- FXR-TGR5 pathway activation
- Inflammatory mediator reduction
- Liver-gut axis modulation
Storage & Handling
- Store at -20°C
- Protect from light
- Available in research quantities
- Stability data provided
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific HPLC profiles
- Research-grade documentation
For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.
Note: This product is intended for laboratory research purposes only.