Description
High-purity Tanshinone IIA (Tan IIA), a bioactive diterpenoid quinone isolated from Salvia miltiorrhiza (Danshen), demonstrating significant cardiovascular, anti-cancer, and neuroprotective properties.
Technical Specifications
- Molecular Formula: C₁₉H₁₈O₃
- Molecular Weight: 294.3 g/mol
- Purity: ≥98% (HPLC)
- Appearance: Red crystalline powder
- Solubility: Soluble in DMSO, ethanol; poorly soluble in water
IUPAC Name: 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
InChI: InChI=1S/C19H18O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,9H,4-5,8H2,1-3H3
InChIKey: HYXITZLLTYIPOF-UHFFFAOYSA-N
Canonical SMILES: CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
Isomeric SMILES: CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
Synonyms: Tanshinone IIA; 568-72-9; Tanshinone II; Dan Shen Ketone; Tanshinone B; Tanshinon II; 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione; UNII-4GPC9FQG6L; …
Botanical Source: Salviae Miltiorrhizae Radix et Rhizoma
Key Features & Benefits
- Natural diterpenoid quinone
- Multiple pharmacological effects
- Strong anti-inflammatory properties
- Comprehensive Certificate of Analysis
Research Applications
-
Cardiovascular Research
- Heart disease studies
- Vascular protection
- Anti-atherosclerotic research
- Cardioprotection mechanisms
-
Cancer Studies
- Anti-proliferative research
- Apoptosis mechanisms
- Drug resistance studies
- Cancer cell signaling
-
Neurodegenerative Research
- Neuroprotection studies
- Cognitive function research
- Neurodegenerative diseases
- Brain protection mechanisms
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Key Research Areas
-
Disease Applications
- Cardiovascular diseases
- Cancer therapy
- Neurodegenerative conditions
- Diabetes and obesity
-
Molecular Mechanisms
- Anti-inflammatory pathways
- Antiproliferative effects
- Antiapoptotic mechanisms
- Antioxidative stress
Biological Activities
- Cardiovascular protection
- Anti-cancer effects
- Neuroprotection
- Anti-inflammatory properties
This premium-grade Tanshinone IIA is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development.
For research and development purposes only. Not for human consumption or clinical use.