Description

IUPAC Name: (3S,4R,4aR)-4-ethenyl-4a-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one

InChI: InChI=1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,15-,16+/m0/s1

InChIKey: HEYZWPRKKUGDCR-QBXMEVCASA-N

Canonical SMILES: C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O

Isomeric SMILES: C=C[C@H]1[C@@H](OC=C2[C@]1(CCOC2=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

Synonyms: Swertiamarin; 17388-39-5; Swertiamarine; Swertiamaroside; SWERTAMARIN; UNII-4038595T7Y; BRN 0055278; Swertimarine; …

Botanical Source: Swertia bimaculata

Product Overview

High-purity Swertiamarin, a natural secoiridoid glycoside isolated from Swertia species and Enicostemma littorale, is manufactured to exceptional standards for pharmaceutical and metabolic research.

Technical Specifications

• Molecular Formula: C₁₆H₂₂O₁₀
• Molecular Weight: 374.34 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White crystalline powder
• Solubility: Soluble in methanol, and water; sparingly soluble in ethanol

Key Features & Benefits

• Natural secoiridoid glycoside
• Potent antidiabetic properties
• Validated structure and activity
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization

Research Applications

1. Metabolic Research

   • Glucose metabolism studies
   • Insulin sensitivity research
   • Lipid metabolism investigations
   • AMPK pathway studies

2. Pharmaceutical Development

   • Antidiabetic research
   • Hepatoprotective studies
   • Anti-inflammatory investigations
   • Drug discovery screening

3. Mechanism Studies

   • Cell signaling pathways
   • Glucose uptake mechanisms
   • PPARγ modulation
   • Molecular target identification

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Diabetes Research

   • Type 2 diabetes studies
   • Insulin resistance
   • Glucose homeostasis
   • β-cell function

2. Liver Protection

   • Hepatic glucose metabolism
   • Oxidative stress
   • Liver enzyme modulation
   • Hepatoprotective mechanisms

3. Anti-inflammatory Effects

   • NF-κB pathway
   • Cytokine modulation
   • Inflammatory mediators
   • Oxidative stress

This premium-grade Swertiamarin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]