Shikonin

SKU 517-89-5 Category

$65.00

CAS No.: 517-89-5
Molecular Formula C₁₆H₁₆O₅
Molecular Weight 288.29g/mol
Purity HPLC>98%
Chemical Family Quinones

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione

InChI: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1

InChIKey: NEZONWMXZKDMKF-SNVBAGLBSA-N

Canonical SMILES: CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C

Isomeric SMILES: CC(=CC[C@H](C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C

Synonyms: shikonin; 517-89-5; Isoarnebin 4; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione; Tokyo Violet; (R)-(+)-Shikonin; Shikonin S; (+)-Shikonin; …

Botanical Source: Arnebiae radix


Product Overview

BIORLAB presents high-purity Shikonin, a natural naphthoquinone pigment with significant applications in cancer research, anti-inflammatory studies, and wound healing investigations.

Technical Specifications

  • Chemical Class: Naphthoquinone derivative
  • Molecular Formula: C₁₆H₁₆O₅
  • Purity: ≥98% (HPLC)
  • Storage: -20°C, protected from light

Key Research Applications

Primary Research Areas

  1. Cancer Studies

    • Cell proliferation inhibition
    • Migration suppression
    • Apoptosis induction
    • Autophagy/necroptosis activation
  2. Anti-inflammatory Research

    • Inflammatory pathway modulation
    • Cytokine regulation
    • Immune response studies

Additional Applications

  • Wound healing research
  • Food packaging studies
  • Antimicrobial investigations
  • Antioxidant research

Research Significance

Cancer Research Mechanisms

  • ROS generation triggering
  • Exosome release suppression
  • Anti-tumor immunity activation
  • Multiple pathway modulation (PI3K/AKT/mTOR, MAPKs)

Molecular Targets

  • TrxR1, PKM2, RIP1/3
  • Src and FAK
  • ERP57, MMPs
  • ATF2, C-MYC, miR-128, GRP78

Properties & Features

  1. Physical Properties

    • Halochromic characteristics
    • pH-sensitive color change
    • Antimicrobial activity
    • Antioxidant properties
  2. Applications

    • Active food packaging
    • Intelligent packaging
    • pH monitoring
    • Antimicrobial protection

Storage & Handling

  • Store at -20°C
  • Protect from light
  • Available in research quantities
  • Stability data provided

Quality Assurance

  • Full spectroscopic characterization
  • Comprehensive Certificate of Analysis
  • Batch-specific HPLC profiles
  • Research-grade documentation

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.


Note: This product is intended for laboratory research purposes only.

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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What Our Client Say

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Carol C Medical Research

Their high-quality natural products have significantly advanced our research, providing us with reliable and consistent results. BIORLAB's commitment to excellence ensures we can push the boundaries of our studies with confidence.

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BIORLAB's solutions in pharmaceutical products are unparalleled. Their innovative approaches and top-notch compounds have revolutionized our development processes, making them an indispensable partner in our pursuit of groundbreaking discoveries.

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The natural compounds from BIORLAB are always pure and effective, ensuring the highest standards in our research. Their dedication to quality and consistency sets them apart, making them our go-to source for natural pharmaceutical ingredients.

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