Description

IUPAC Name: (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

InChI: InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

InChIKey: IPQVTOJGNYVQEO-AIFLABODSA-N

Canonical SMILES: C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Isomeric SMILES: C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C([C@@H]2[C@H]5C6=C(C(=CC=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Synonyms: Sennoside B; 128-57-4; MLS002473001; CHEBI:34975; MFCD00151528; F887D1637W; (9R,9’S)-4,4′-dihydroxy-10,10′-dioxo-5,5′-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9′,10,10′-tetrahydro-[9,9′-bianthracene]-2,2′-dicarboxylic acid; SMR001397106; …

Botanical Source: Sennae Folium

Product Overview

Sennoside B is a bioactive anthraquinone glycoside with significant pharmacological properties. BIORLAB provides high-purity sennoside B isolated through advanced chromatographic techniques and validated analytical methods for pharmaceutical research applications.

Technical Specifications

• Molecular Formula: C₄₂H₃₈O₂₀
• Molecular Weight: 862.7 g/mol
• Appearance: Yellow to brown crystalline powder
• Solubility: Soluble in water, DMSO; slightly soluble in ethanol
• Melting Point: >250°C (decomposition)

Storage and Handling

• Store at -20°C in sealed containers
• Protect from light and moisture
• Stability: 2 years when properly stored
• Stock solution: Prepare in DMSO or water
• Avoid repeated freeze-thaw cycles

Key Research Applications

Gastrointestinal Research

• Intestinal motility studies
• Secretory mechanisms
• Mucosal transport
• Gut microbiota interactions

Metabolic Studies

• Glucoside metabolism
• Enzyme activation research
• Bioavailability studies
• Metabolic transformation

Pharmaceutical Development

• Drug formulation research
• Stability studies
• Bioactivity assessments
• Structure-activity relationships

Quality Assurance

• HPLC purity analysis
• Structure verified by NMR
• Complete Certificate of Analysis
• Batch-specific documentation
• Stringent quality control

Research Benefits

• High biological activity
• Excellent batch consistency
• Comprehensive documentation
• Enhanced stability
• Superior purity

Research Applications Highlights

1. Gastrointestinal Studies

   • Peristalsis mechanisms
   • Ion transport
   • Mucosal function
   • Epithelial barrier research

2. Metabolic Research

   • Pro-drug activation
   • Enzymatic conversion
   • Absorption mechanisms
   • Biotransformation

3. Pharmaceutical Applications

   • Formulation development
   • Stability assessment
   • Bioavailability studies
   • Drug delivery systems

Why Choose BIORLAB’s Sennoside B?

• Industry-leading purity standards
• Expert technical support
• Full analytical documentation
• Competitive Pricing
• Global shipping capability
• Custom synthesis options

Technical Support

• Method development assistance
• Analytical protocols
• Stability data
• Storage recommendations
• Application Guidance

For research use only. Not for human consumption or therapeutic use.