Description

IUPAC Name: (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

InChI: InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

InChIKey: IPQVTOJGNYVQEO-KGFNBKMBSA-N

Canonical SMILES: C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Isomeric SMILES: C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C([C@@H]2[C@@H]5C6=C(C(=CC=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

Synonyms: Sennoside A; 81-27-6; 8013-11-4; Dosaflex; Gentlax; Sennalax; Senokot; Senolax; …

Botanical Source: Sennae Folium

BIORLAB offers high-purity sennosides, naturally derived from Senna alexandrina (Cassia senna). Our pharmaceutical-grade sennosides meet stringent quality standards for research, pharmaceutical development, and natural product formulation, supporting both traditional medicine validation and modern drug development.

Technical Specifications

• Molecular Formula: C₄₂H₃₈O₂₀
• CAS Numbers: 81-27-6
• Purity: ≥98%
• Appearance: Yellow to brown crystalline powder
• Solubility: Soluble in water and methanol

Key Features and Benefits

• Premium Quality: Advanced extraction and purification technology
• Standardized Content: Precise sennoside A & B ratio
• Full Characterization: Complete analytical documentation
• Batch Consistency: Rigorous quality control procedures
• Natural Source: Sustainably harvested botanical material

Research Applications

• Pharmaceutical Development: Gastrointestinal drug research
• Natural Product Studies: Traditional medicine validation
• Mechanism Studies: Gut motility research
• Bioavailability Research: Absorption and metabolism studies
• Formulation Development: Novel delivery systems

Industry Applications

• Pharmaceutical R&D
• Natural Product Development
• Traditional Medicine Research
• Clinical Studies
• Botanical Drug Development

Quality Assurance

Each batch undergoes comprehensive testing:

• Content determination by HPLC
• Identity confirmation through multiple methods
• Heavy metal analysis
• Residual solvent testing
• Microbial limit testing
• Stability studies

Storage and Handling

• Store at room temperature
• Protect from light and moisture
• Shelf life: 36 months when properly stored
• Available in research and bulk quantities
• Humidity-resistant packaging

Innovation Potential

Our sennosides support research in:

• Novel pharmaceutical formulations
• Controlled-release technologies
• Natural product development
• Bioavailability enhancement
• Traditional medicine validation

Regulatory Compliance

• Manufactured in ISO-certified facilities
• Follows USP/EP pharmacopeia standards
• Complete documentation available
• Meets international GMP requirements
• Suitable for research purposes

Research-Backed Properties

• Characterized Mechanism of Action
• Established Pharmacokinetics
• Well-Documented Safety Profile
• Standardized Potency
• Verified Botanical Identity

Contact BIORLAB’s technical support team for detailed specifications, custom requirements, or bulk ordering information.