Description

High-purity Salvianolic Acid B (SAB), a water-soluble phenolic acid isolated from Salvia miltiorrhiza (Danshen), demonstrating significant antioxidant, cardiovascular protective, and neuroprotective properties.

Technical Specifications

• Molecular Formula: C₃₆H₃₀O₁₆
• Molecular Weight: 718.6 g/mol
• Purity: ≥98% (HPLC)
• Appearance: Yellow to light brown powder
• Solubility: Highly soluble in water and methanol; soluble in ethanol

IUPAC Name: (2R)-2-[(E)-3-[(2S,3S)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoic acid

InChI: InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31+,32-/m1/s1

InChIKey: SNKFFCBZYFGCQN-VWUOOIFGSA-N

Canonical SMILES: C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)OC(CC5=CC(=C(C=C5)O)O)C(=O)O)O)O

Isomeric SMILES: C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=C3[C@@H]([C@H](OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)O[C@H](CC5=CC(=C(C=C5)O)O)C(=O)O)O)O

Synonyms: Salvianolic acid B; Lithospermic acid B; 121521-90-2; Dan Shen Suan B; Danfensuan B; Monardic acid B; 115939-25-8; UNII-C1GQ844199; …

Botanical Source: Salviae Miltiorrhizae Radix et Rhizoma

Key Features & Benefits

• Natural polyphenolic compound
• Strong antioxidant activity
• Cardiovascular protection
• Neuroprotective properties
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization

Research Applications

1. Cardiovascular Research

   • Endothelial function studies
   • Anti-thrombotic research
   • Vascular protection
   • Cardiac fibrosis prevention

2. Neuroscience Studies

   • Neuroprotection mechanisms
   • Blood-brain barrier research
   • Cognitive function studies
   • Neural cell protection

3. Antioxidant Research

   • Free radical scavenging
   • Oxidative stress protection
   • Cellular defense mechanisms
   • Mitochondrial function

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions
• Reconstitution protocols available

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Package Sizes

• 5mg
• 10mg
• 25mg
• 100mg
• Bulk quantities available

Key Research Areas

1. Cardiovascular Protection

   • Atherosclerosis prevention
   • Endothelial function
   • Platelet aggregation
   • Vascular inflammation

2. Neuroprotection

   • Cerebral ischemia
   • Neurodegenerative diseases
   • Cognitive enhancement
   • Neural repair

3. Fibrosis Research

   • Organ fibrosis
   • ECM regulation
   • TGF-β pathway
   • Fibroblast activation

Biological Activities

• Antioxidant effects (EC50 documented)
• Anti-inflammatory properties
• Anti-fibrotic activity
• Neuroprotective functions

This premium-grade Salvianolic Acid B is designed for research institutions and pharmaceutical companies advancing therapeutic development.

For research and development purposes only. Not for human consumption or clinical use.