Original price was: $571.00.$457.00Current price is: $457.00.
| CAS No.: | 3774-64-9 |
| Molecular Formula | C₁₆H₁₂O₅ |
| Molecular Weight | 284.26 g/mol |
| Purity | HPLC≥97.5% |
| Chemical Family | Quinones |
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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.
Questin, extracted from the seeds of *Cassia obtusifolia*, is a Cdc25B phosphatase inhibitor with an IC50 value of 34 µg/mL. It is a promising inhibitor of AChE, BChE, and BACE1. Questin strongly inhibits the growth of human colon cancer cells, SW620, with a GI50 value of 0.9 µg/mL. It exhibits significantly high immunosuppressive activity and has potential as a therapeutic or preventive agent for Alzheimer’s disease. However, Questin is toxic to the human A549 lung cell line.
IUPAC Name: 1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione
InChI: InChI=1S/C16H12O5/c1-7-3-9-13(11(18)4-7)16(20)14-10(15(9)19)5-8(17)6-12(14)21-2/h3-6,17-18H,1-2H3
InChIKey: UUNPIWCQMVNINR-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3OC)O
Synonyms: Questin; 3774-64-9; 1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione; Emodin-8-methyl ether; 9,10-Anthracenedione,1,6-dihydroxy-8-methoxy-3-methyl-; CHEBI:16200; 7Z6321X03I; 1,6-dihydroxy-8-methoxy-3-methylanthraquinone; …
Botanical Source:
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