Podofilox

SKU 518-28-5 Category

$30.00

CAS No.: 518-28-5
Molecular Formula C₂₂H₂₂O₈
Molecular Weight 414.4g/mol
Purity HPLC>98%
Chemical Family Lignans

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

InChI: InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1

InChIKey: YJGVMLPVUAXIQN-XVVDYKMHSA-N

Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

Isomeric SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O

Synonyms: podophyllotoxin; Podofilox; 518-28-5; Condylox; Condyline; (-)-Podophyllotoxin; Podophyllotoxin 7; Podophyllinic acid lactone; …

Botanical Source: Dysosma versipellis


Podofilox, also known as podophyllotoxin, is a naturally occurring cytotoxic lignan extracted from Podophyllum plants. BIORLAB offers pharmaceutical-grade podofilox with guaranteed >98% purity, making it ideal for research and drug development applications.

Chemical Properties

– Molecular Formula: C₂₂H₂₂O₈
– CAS Number: 518-28-5
– Molecular Weight: 414.4 g/mol
– Appearance: White to off-white crystalline powder
– Solubility: Soluble in organic solvents

Applications in Pharmaceutical Research

– Antiviral drug development
– Cancer research and cytotoxicity studies
– Development of topical medications
– Investigation of cell cycle inhibition mechanisms
– Research into anti-proliferative compounds

Key Benefits

– High purity (>98%) verified by HPLC
– Naturally sourced compound
– Well-characterized biological activity
– Established safety profile
– Suitable for pharmaceutical R&D

Research Areas

Podofilox has shown promising potential in:
– Oncology research
– Dermatological drug development
– Anti-viral therapeutic studies
– Cell biology investigations
– Medicinal chemistry research

Quality Assurance

Each batch undergoes rigorous testing for:
– Chemical purity
– Structural verification
– Biological activity
– Stability assessment
– Contaminant screening

Storage and Handling

– Store at -20°C
– Protect from light and moisture
– Stable for 2 years when properly stored
– Available in research-grade quantities

Contact BIORLAB for detailed specifications and bulk ordering information. Our technical support team is available to assist with your research needs.

Additional information

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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