Description
IUPAC Name: (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
InChI: InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChIKey: YJGVMLPVUAXIQN-XVVDYKMHSA-N
Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
Isomeric SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O
Synonyms: podophyllotoxin; Podofilox; 518-28-5; Condylox; Condyline; (-)-Podophyllotoxin; Podophyllotoxin 7; Podophyllinic acid lactone; …
Botanical Source: Dysosma versipellis
Podofilox, also known as podophyllotoxin, is a naturally occurring cytotoxic lignan extracted from Podophyllum plants. BIORLAB offers pharmaceutical-grade podofilox with guaranteed >98% purity, making it ideal for research and drug development applications.
Chemical Properties
– Molecular Formula: C₂₂H₂₂O₈
– CAS Number: 518-28-5
– Molecular Weight: 414.4 g/mol
– Appearance: White to off-white crystalline powder
– Solubility: Soluble in organic solvents
Applications in Pharmaceutical Research
– Antiviral drug development
– Cancer research and cytotoxicity studies
– Development of topical medications
– Investigation of cell cycle inhibition mechanisms
– Research into anti-proliferative compounds
Key Benefits
– High purity (>98%) verified by HPLC
– Naturally sourced compound
– Well-characterized biological activity
– Established safety profile
– Suitable for pharmaceutical R&D
Research Areas
Podofilox has shown promising potential in:
– Oncology research
– Dermatological drug development
– Anti-viral therapeutic studies
– Cell biology investigations
– Medicinal chemistry research
Quality Assurance
Each batch undergoes rigorous testing for:
– Chemical purity
– Structural verification
– Biological activity
– Stability assessment
– Contaminant screening
Storage and Handling
– Store at -20°C
– Protect from light and moisture
– Stable for 2 years when properly stored
– Available in research-grade quantities
Contact BIORLAB for detailed specifications and bulk ordering information. Our technical support team is available to assist with your research needs.