Description
IUPAC Name: 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one
InChI: InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
InChIKey: VABYUUZNAVQNPG-BQYQJAHWSA-N
Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O
Isomeric SMILES: COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O
Synonyms: Piperlongumine; Piplartine; 20069-09-4; UNII-SGD66V4SVJ; SGD66V4SVJ; (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; CHEBI:8241; 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-; …
Botanical Source:
Product Overview
Piperlongumine is a bioactive alkaloid naturally extracted from Long pepper (Piper longum L.), renowned for its significant research applications in pharmaceutical development. BIORLAB provides high-purity piperlongumine isolated through advanced separation techniques and validated analytical methods.
Technical Specifications
- Molecular Formula: C₁₇H₁₉NO₅
- Molecular Weight: 317.34 g/mol
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in DMSO, methanol, ethanol
- Melting Point: 122-124°C
Storage and Handling
- Store at -20°C in sealed containers
- Protect from light and moisture
- Stability: 2 years when properly stored
- Solution stability: 24 hours at room temperature
- Handle with appropriate safety measures
Key Research Applications
Cancer Research
- Cell proliferation studies
- Apoptosis mechanism investigation
- Selective cytotoxicity research
- ROS modulation studies
- Cancer cell resistance research
Molecular Biology
- Signal transduction studies
- Protein interaction research
- Gene expression analysis
- Cellular stress response studies
Therapeutic Investigation
- Anti-inflammatory research
- Antioxidant activity studies
- Drug resistance modulation
- Novel drug development
Quality Assurance
- Advanced HPLC analysis
- Structure confirmed by 1H-NMR and 13C-NMR
- Comprehensive Certificate of Analysis
- Batch-specific quality documentation
- Rigorous purity testing
Research Benefits
- Exceptional batch consistency
- High biological activity
- Suitable for in vitro and in vivo research
- Comprehensive technical documentation
- Enhanced stability formulation
Why Choose BIORLAB’s Piperlongumine?
- Industry-leading purity standards
- Expert technical support
- Full analytical documentation
- Competitive Pricing
- Global shipping capability
- Custom synthesis options
Research Applications Highlights
-
Cancer Research
- Selective targeting of cancer cells
- Studies on drug-resistant cancers
- Cancer stem cell research
-
Cellular Mechanisms
- ROS-dependent cytotoxicity
- Glutathione depletion studies
- Stress response pathways
-
Drug Development
- Lead compound optimization
- Structure-activity relationship studies
- Drug combination research
For research and laboratory use only. Not for human consumption, diagnostic or therapeutic use.