Piperlongumine

SKU 20069-09-4 Category

$75.00

CAS No.: 20069-09-4
Molecular Formula C₁₇H₁₉NO₅
Molecular Weight 317.34g/mol
Purity HPLC>98%
Chemical Family Alkaloids

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one

InChI: InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChIKey: VABYUUZNAVQNPG-BQYQJAHWSA-N

Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O

Isomeric SMILES: COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O

Synonyms: Piperlongumine; Piplartine; 20069-09-4; UNII-SGD66V4SVJ; SGD66V4SVJ; (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; CHEBI:8241; 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-; …

Botanical Source:


Product Overview

Piperlongumine is a bioactive alkaloid naturally extracted from Long pepper (Piper longum L.), renowned for its significant research applications in pharmaceutical development. BIORLAB provides high-purity piperlongumine isolated through advanced separation techniques and validated analytical methods.

Technical Specifications

  • Molecular Formula: C₁₇H₁₉NO₅
  • Molecular Weight: 317.34 g/mol
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in DMSO, methanol, ethanol
  • Melting Point: 122-124°C

Storage and Handling

  • Store at -20°C in sealed containers
  • Protect from light and moisture
  • Stability: 2 years when properly stored
  • Solution stability: 24 hours at room temperature
  • Handle with appropriate safety measures

Key Research Applications

Cancer Research

  • Cell proliferation studies
  • Apoptosis mechanism investigation
  • Selective cytotoxicity research
  • ROS modulation studies
  • Cancer cell resistance research

Molecular Biology

  • Signal transduction studies
  • Protein interaction research
  • Gene expression analysis
  • Cellular stress response studies

Therapeutic Investigation

  • Anti-inflammatory research
  • Antioxidant activity studies
  • Drug resistance modulation
  • Novel drug development

Quality Assurance

  • Advanced HPLC analysis
  • Structure confirmed by 1H-NMR and 13C-NMR
  • Comprehensive Certificate of Analysis
  • Batch-specific quality documentation
  • Rigorous purity testing

Research Benefits

  • Exceptional batch consistency
  • High biological activity
  • Suitable for in vitro and in vivo research
  • Comprehensive technical documentation
  • Enhanced stability formulation

Why Choose BIORLAB’s Piperlongumine?

  • Industry-leading purity standards
  • Expert technical support
  • Full analytical documentation
  • Competitive Pricing
  • Global shipping capability
  • Custom synthesis options

Research Applications Highlights

  1. Cancer Research

    • Selective targeting of cancer cells
    • Studies on drug-resistant cancers
    • Cancer stem cell research
  2. Cellular Mechanisms

    • ROS-dependent cytotoxicity
    • Glutathione depletion studies
    • Stress response pathways
  3. Drug Development

    • Lead compound optimization
    • Structure-activity relationship studies
    • Drug combination research

For research and laboratory use only. Not for human consumption, diagnostic or therapeutic use.

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

Testimonials

What Our Client Say

BIORLAB is committed to providing highly competitive natural compounds and comprehensive solutions to customers around the world.

Carol C Medical Research

Their high-quality natural products have significantly advanced our research, providing us with reliable and consistent results. BIORLAB's commitment to excellence ensures we can push the boundaries of our studies with confidence.

Chester Glass Medical Research

BIORLAB's solutions in pharmaceutical products are unparalleled. Their innovative approaches and top-notch compounds have revolutionized our development processes, making them an indispensable partner in our pursuit of groundbreaking discoveries.

Julian K Medical Research

The natural compounds from BIORLAB are always pure and effective, ensuring the highest standards in our research. Their dedication to quality and consistency sets them apart, making them our go-to source for natural pharmaceutical ingredients.

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