Description

High-purity Oridonin, a natural diterpenoid isolated from Rabdosia rubescens, is manufactured to exceptional standards for cancer research and pharmaceutical studies.

Technical Specifications

• Molecular Formula: C₂₀H₂₈O₆
• Molecular Weight: 364.4 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White crystalline powder
• Solubility: Soluble in DMSO, methanol; sparingly soluble in water

IUPAC Name: (1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

InChI: InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

InChIKey: SDHTXBWLVGWJFT-XKCURVIJSA-N

Canonical SMILES: CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C

Isomeric SMILES: CC1(CC[C@@H]([C@]23[C@@H]1[C@@H]([C@]([C@]45[C@H]2CC[C@H]([C@H]4O)C(=C)C5=O)(OC3)O)O)O)C

Synonyms: Oridonin; 28957-04-2; Oridonine; ISODONOL; Rubescensin A; 0APJ98UCLQ; lasidonin; CHEMBL1164920; …

Botanical Source: Rabdosia rubescens

Key Features & Benefits

• Natural diterpenoid compound
• Potent anti-tumor activity
• Multi-target pharmacological effects
• Low side effects
• Comprehensive Certificate of Analysis

Research Applications

1. Cancer Research

   • Apoptosis studies
   • Survival signaling investigations
   • Cancer cell line testing
   • Drug resistance studies

2. Pharmaceutical Development

   • Anti-tumor research
   • Anti-bacterial studies
   • Anti-inflammatory investigations
   • Immunomodulatory research

3. Mechanism Studies

   • Cell signaling pathways
   • Molecular target identification
   • Drug resistance mechanisms
   • Combination therapy research

Modern Pharmacological Effects

• Anti-tumor activity
• Anti-bacterial properties
• Anti-inflammatory effects
• Anti-oxidant capabilities
• Cardiovascular protection
• Immunomodulatory functions

Storage & Handling

• Store at -20°C
• Protect from light
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Cancer Biology

   • Apoptosis mechanisms
   • Cell survival pathways
   • Drug resistance
   • Combination strategies

2. Multi-target Effects

   • Anti-inflammatory pathways
   • Immunomodulation
   • Oxidative stress
   • Cardiovascular protection

3. Drug Development

   • Novel drug design
   • Structure-activity relationships
   • Therapeutic applications
   • Clinical potential

This premium-grade Oridonin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]