Description

IUPAC Name: (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol

InChI: InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1

InChIKey: UQRORFVVSGFNRO-UTINFBMNSA-N

Canonical SMILES: CCCCN1CC(C(C(C1CO)O)O)O

Isomeric SMILES: CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O

Synonyms: Miglustat; 72599-27-0; Zavesca; N-Butyldeoxynojirimycin; Butyldeoxynojirimycin; N-Butylmoranoline; NB-DNJ; (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol; …

Botanical Source:

Product Overview

BIORLAB provides high-purity Miglustat (≥98%), a synthetic analog of D-glucose targeting UDP-glucose ceramide glucosyltransferase (UGCG), with significant applications in Gaucher disease, Niemann-Pick disease type C, and other metabolic disorder research.

Technical Specifications

• Molecular Formula: C₁₀H₂₁NO₄
• Molecular Weight: 219.28 g/mol
• Appearance: White crystalline powder
• Purity: ≥98% (HPLC)
• Solubility: Water-soluble
• Storage: Room temperature, sealed dry

Research Applications

Primary Research Areas

• Lysosomal storage disorders
• Glycosphingolipid metabolism
• Drug development studies
• Neurologic manifestations

Key Research Areas

1. Disease Studies

   • Gaucher disease
   • Niemann-Pick disease type C
   • Glycogen storage disease
   • Metabolic disorders

2. Molecular Research

   • UGCG enzyme inhibition
   • Ceramide metabolism
   • Cell signaling
   • Drug transport

Research Significance

1. Biological Activities

   • UGCG inhibition
   • Glycosphingolipid reduction
   • Metabolic modulation
   • Cellular trafficking

2. Therapeutic Applications

   • Nervous system diseases
   • Congenital disorders
   • Endocrine diseases
   • Metabolic conditions

Storage & Handling

• Store at room temperature
• Keep sealed dry
• Available in research quantities
• Stability data provided
• Special handling protocols available

Quality Assurance

• Full spectroscopic characterization
• Comprehensive Certificate of Analysis
• Batch-specific HPLC profiles
• Stability testing data
• Research-grade documentation

Target Applications

• Metabolic research centers
• Drug development facilities
• Neuroscience laboratories
• Academic research institutions

Technical Support Features

• Method development assistance
• Analytical testing guidance
• Stability data available
• Research protocol support
• Documentation assistance

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.

Note: This product is intended for laboratory research purposes only.