Description
IUPAC Name: (1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
InChI: InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1
InChIKey: ZSBXGIUJOOQZMP-JLNYLFASSA-N
Canonical SMILES: C1CC2C3CCCN4C3C(CCC4)CN2C(=O)C1
Isomeric SMILES: C1C[C@@H]2[C@H]3CCCN4[C@H]3[C@@H](CCC4)CN2C(=O)C1
Synonyms: Matrine; 519-02-8; (+)-Matrine; Matridin-15-one; Vegard; alpha-Matrine; Matrene, (+)-; (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one; …
Botanical Source: Sophora flavescens Ait.
Matrine (CAS: 519-02-8) | Premium Alkaloid Research Compound
Technical Specifications
- Molecular Formula: C₁₅H₂₄N₂O
- Molecular Weight: 248.36
- Appearance: White crystalline powder
- Melting Point: 77°C
- Boiling Point: 86-88°C/2.5Torr
Physical Properties
- LogP: 1.440 (est)
- Solubility: Up to 25 mg/ml in water
- Optical Activity: +37.926 (c 1.69, H2O)
- Density: 1.191g/cm
- Refractive Index: 1.536
Research Applications
Primary Research Areas
-
Cancer Research
- Anti-proliferative effects
- Gastric cancer cell line studies
- NSCLC cell research
- Apoptosis induction
-
Cardiovascular Studies
- Antiarrhythmic effects
- Myocardial protection
- Heart rate regulation
- PR and QTC interval extension
Clinical Applications
-
Therapeutic Uses
- Chronic active hepatitis
- Trichomoniasis
- Candida vaginitis
- Chronic cervicitis
-
Additional Uses
- Senile vaginitis
- Pelvic inflammatory disease
- Liver injury
- Liver fibrosis
Pharmacological Effects
-
Cardiovascular System
- Negative frequency effects
- Positive inotropic action
- Enhanced myocardial contractility
- Heart rate reduction
-
Molecular Actions
- BCL-2 gene expression promotion
- BCL-2/Bax ratio improvement
- Myocardial cell apoptosis inhibition
- Anti-pulmonary fibrosis effects
Storage & Stability
- Store at 2-8°C
- Seal in dry conditions
- Stable for 1 year
- Solutions stable at -20°C for 3 months
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific profiles
- Research-grade documentation
For detailed technical information, bulk quantities, or custom requirements, contact the BIORLAB support team.
Note: This product is intended for laboratory research purposes only.