Description
High-purity Lucidin, a natural anthraquinone compound with documented mutagenic and DNA-modifying properties, isolated from Rubia tinctorum L.
Technical Specifications
- Molecular Formula: C₁₅H₁₀O₅
- CAS Number: 478-08-0
- Chemical Name: 1,3-dihydroxy-2-(hydroxymethyl)anthraquinone
- Appearance: Light yellow to yellow crystalline powder
- Solubility: Soluble in DMSO
IUPAC Name: 1,3-dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione
InChI: InChI=1S/C15H10O5/c16-6-10-11(17)5-9-12(15(10)20)14(19)8-4-2-1-3-7(8)13(9)18/h1-5,16-17,20H,6H2
InChIKey: AMIDUPFSOUCLQB-UHFFFAOYSA-N
Canonical SMILES: C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)CO)O
Isomeric SMILES: C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)CO)O
Synonyms: Lucidin; 478-08-0; Henine; 1,3-dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione; Lucidin (quinone); 1,3-Dihydroxy-2-(hydroxymethyl)anthraquinone; NSC 30546; CCRIS 1642; …
Botanical Source:
Physical Properties
- Melting Point: >330°C
- Boiling Point: 333.35°C (estimated)
- Density: 1.592±0.06 g/cm3 (20ºC, 760 Torr)
- Refractive Index: 1.6000 (estimated)
- pKa: 6.83±0.20 (Predicted)
Biological Activity
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Mutagenic Effects
- Active in Salmonella typhimurium strains
- Mutagenic at HGPRT gene locus
- Induces DNA single-strand breaks
- Causes DNA-protein cross-links
-
DNA Modification
- Induces DNA repair synthesis
- Active in primary rat hepatocytes
- Transforms C3H/M2-mouse fibroblasts
- Shows genotoxic properties
Research Applications
-
Mutagenicity Studies
- Bacterial mutation assays
- Mammalian cell studies
- DNA repair investigations
- Genotoxicity research
-
Cell Biology Research
- DNA damage studies
- Cell transformation assays
- Repair mechanism research
- Toxicology investigations
Storage & Handling
- Store at room temperature
- Keep sealed and dry
- Protect from light
- Follow safety protocols
- Use appropriate PPE
Quality Control
- Identity verification
- Purity assessment
- Structure confirmation
- Stability monitoring
- Analytical documentation
For research purposes only. Not for human, veterinary, or agricultural use.