Lucidin

SKU 478-08-0 Category

$96.00$165.00

CAS No.: 478-08-0
Molecular Formula C₁₅H₁₀O₅
Molecular Weight 270.24g/mol
Purity HPLC>98%
Chemical Family Anthraquinones

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Description


High-purity Lucidin, a natural anthraquinone compound with documented mutagenic and DNA-modifying properties, isolated from Rubia tinctorum L.

Technical Specifications

  • Molecular Formula: C₁₅H₁₀O₅
  • CAS Number: 478-08-0
  • Chemical Name: 1,3-dihydroxy-2-(hydroxymethyl)anthraquinone
  • Appearance: Light yellow to yellow crystalline powder
  • Solubility: Soluble in DMSO

 

IUPAC Name: 1,3-dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione

InChI: InChI=1S/C15H10O5/c16-6-10-11(17)5-9-12(15(10)20)14(19)8-4-2-1-3-7(8)13(9)18/h1-5,16-17,20H,6H2

InChIKey: AMIDUPFSOUCLQB-UHFFFAOYSA-N

Canonical SMILES: C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)CO)O

Isomeric SMILES: C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)CO)O

Synonyms: Lucidin; 478-08-0; Henine; 1,3-dihydroxy-2-(hydroxymethyl)anthracene-9,10-dione; Lucidin (quinone); 1,3-Dihydroxy-2-(hydroxymethyl)anthraquinone; NSC 30546; CCRIS 1642; …

Botanical Source:


 

Physical Properties

  • Melting Point: >330°C
  • Boiling Point: 333.35°C (estimated)
  • Density: 1.592±0.06 g/cm3 (20ºC, 760 Torr)
  • Refractive Index: 1.6000 (estimated)
  • pKa: 6.83±0.20 (Predicted)

Biological Activity

  1. Mutagenic Effects

    • Active in Salmonella typhimurium strains
    • Mutagenic at HGPRT gene locus
    • Induces DNA single-strand breaks
    • Causes DNA-protein cross-links
  2. DNA Modification

    • Induces DNA repair synthesis
    • Active in primary rat hepatocytes
    • Transforms C3H/M2-mouse fibroblasts
    • Shows genotoxic properties

Research Applications

  1. Mutagenicity Studies

    • Bacterial mutation assays
    • Mammalian cell studies
    • DNA repair investigations
    • Genotoxicity research
  2. Cell Biology Research

    • DNA damage studies
    • Cell transformation assays
    • Repair mechanism research
    • Toxicology investigations

Storage & Handling

  • Store at room temperature
  • Keep sealed and dry
  • Protect from light
  • Follow safety protocols
  • Use appropriate PPE

Quality Control

  • Identity verification
  • Purity assessment
  • Structure confirmation
  • Stability monitoring
  • Analytical documentation

For research purposes only. Not for human, veterinary, or agricultural use.

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