Description

IUPAC Name: (1R,2R,7S,10R,13R,14R,16S,19S,20S)-19-(furan-3-yl)-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,12,17-trione

InChI: InChI=1S/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20+,23-,24-,25+,26+/m0/s1

InChIKey: KBDSLGBFQAGHBE-MSGMIQHVSA-N

Canonical SMILES: CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C

Isomeric SMILES: C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C

Synonyms: Limonin; 1180-71-8; Dictamnolactone; Obaculactone; Citrolimonin; Evodin; Limonine; 7,16-Dioxo-7,16-dideoxylimondiol; …

Botanical Source: Aurantii fructus immaturus

Product Overview

High-purity Limonin, a natural limonoid triterpene primarily isolated from Citrus species, is specifically purified for pharmaceutical research, nutraceutical development, and bioactivity studies.

Technical Specifications

• Molecular Formula: C₂₆H₃₀O₈
• Molecular Weight: 470.5 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO, methanol, and ethanol; limited water solubility

Key Features & Benefits

• Natural bioactive triterpene compound
• Advanced isolation and purification
• Validated chemical structure
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization data

Research Applications

1. Pharmaceutical Research

   • Anti-cancer studies
   • Anti-inflammatory investigations
   • Antioxidant research
   • Drug development studies

2. Nutraceutical Development

   • Natural preservative research
   • Functional food applications
   • Bioavailability studies
   • Formulation development

3. Mechanism Studies

   • Cell signaling pathways
   • Apoptosis mechanisms
   • Gene expression research
   • Enzyme inhibition studies

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Solution preparation guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant production
• Rigorous quality control testing
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Regulatory documentation

Key Research Areas

1. Cancer Research

   • Antiproliferative mechanisms
   • Apoptosis induction studies
   • Cancer cell line investigations
   • Drug resistance research

2. Inflammatory Response

   • Cytokine modulation
   • NF-κB pathway studies
   • Anti-inflammatory mechanisms

3. Antioxidant Properties

   • Free radical scavenging
   • Oxidative stress protection
   • Cellular defense mechanisms

This premium-grade Limonin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.