Description

High-purity Kavain, a major kavalactone isolated from Piper methysticum (Kava), is manufactured to exceptional standards for neuroscience and pharmaceutical research.

Technical Specifications

• Molecular Formula:  C₁₄H₁₄O₃
• Molecular Weight: 230.26 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in organic solvents; poorly soluble in water

IUPAC Name: (2R)-4-methoxy-2-[(E)-2-phenylethenyl]-2,3-dihydropyran-6-one

InChI: InChI=1S/C14H14O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-8,10,12H,9H2,1H3/b8-7+/t12-/m0/s1

InChIKey: XEAQIWGXBXCYFX-GUOLPTJISA-N

Canonical SMILES: COC1=CC(=O)OC(C1)C=CC2=CC=CC=C2

Isomeric SMILES: COC1=CC(=O)O[C@H](C1)/C=C/C2=CC=CC=C2

Synonyms: Kawain; kavain; 500-64-1; (+)-Kavain; Gonosan; (R)-(+)-Kavain; Kavain, dl-; Kawaih; …

Botanical Source: Piper methysticum Forst

Key Features & Benefits

• Natural kavalactone
• Anxiolytic properties
• GABAergic modulation
• Validated structure and activity
• Comprehensive Certificate of Analysis

Research Applications

1. Neuroscience Research

   • Anxiety mechanisms
   • GABA receptor studies
   • Voltage-gated ion channels
   • Neurotransmitter modulation

2. Pharmaceutical Development

   • Anxiolytic research
   • Sleep studies
   • Muscle relaxant properties
   • Drug discovery screening

3. Mechanism Studies

   • Ion channel interactions
   • Receptor binding profiles
   • Neurotransmitter systems
   • Pharmacokinetic analysis

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Neural Function

   • Anxiety mechanisms
   • Sleep regulation
   • Muscle relaxation
   • Stress response

2. Receptor Studies

   • GABA modulation
   • Ion channel interactions
   • Neurotransmitter systems
   • Binding profiles

3. Clinical Research

   • Anxiolytic effects
   • Sleep enhancement
   • Muscle tension
   • Stress reduction

This premium-grade Kavain is designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]