Description

IUPAC Name: [(1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] (Z)-2-methylbut-2-enoate

InChI: InChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16+,17-,18+,19-,21+,24+,25+/m1/s1

InChIKey: VDJHFHXMUKFKET-WDUFCVPESA-N

Canonical SMILES: CC=C(C)C(=O)OC1C(=CC23C1(C(C(=CC(C2=O)C4C(C4(C)C)CC3C)CO)O)O)C

Isomeric SMILES: C/C=C(/C)C(=O)O[C@H]1C(=C[C@@]23[C@@]1([C@@H](C(=C[C@H](C2=O)[C@H]4[C@H](C4(C)C)C[C@H]3C)CO)O)O)C

Synonyms: Ingenol mebutate; Ingenol 3-angelate; Picato; 3-Angeloylingenol; 3-Ingenyl angelate; PEP-005; PEP005; 75567-37-2; …

Botanical Source: Euphorbia lathyris L

BIORLAB presents pharmaceutical-grade ingenol mebutate, a bioactive diterpene compound originally derived from Euphorbia peplus. Our highly purified ingenol mebutate supports advanced dermatological research and pharmaceutical development, meeting stringent quality requirements for investigational studies.

Technical Specifications

• Molecular Formula: C₂₅H₃₄O₆
• CAS Number: 75567-37-2
• Purity: ≥98%
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO and ethanol

Key Features and Benefits

• Exceptional Purity: Advanced purification technology ensuring the highest quality
• Full Characterization: Comprehensive analytical documentation including HPLC, NMR, and MS
• Research Grade: Suitable for pharmaceutical development and preclinical studies
• Batch Consistency: Rigorous quality control between productions
• Stability-Optimized: Enhanced storage conditions for maximum shelf life

Research Applications

• Dermatological Research: Skin cell response studies
• Pharmaceutical Development: Novel formulation research
• Cell Signaling Studies: Protein kinase C activation research
• Oncology Research: Cell death pathway investigations
• Drug Delivery: Topical formulation development

Industry Applications

• Pharmaceutical R&D
• Dermatological Research
• Drug Development Programs
• Academic Research
• Clinical Studies

Quality Assurance

Each batch undergoes comprehensive testing:

• Identity confirmation through multiple analytical methods
• Purity verification using validated HPLC protocols
• Structure elucidation via spectroscopic analysis
• Stability assessment under controlled conditions
• Impurity profiling and characterization

Storage and Handling

• Store at -20°C under an inert atmosphere
• Protect from light and moisture
• Shelf life: 24 months when properly stored
• Available in research quantities
• Special handling precautions required

Innovation Potential

Our ingenol mebutate supports research in:

• Novel drug delivery systems
• Targeted therapeutic applications
• Mechanism of action studies
• Pharmacokinetic investigations
• Formulation optimization

Regulatory Compliance

• Manufactured in ISO-certified facilities
• Follows cGMP guidelines
• Complete documentation available
• Meets international pharmacopeia standards
• Suitable for research purposes only

Safety Considerations

• High potency compound
• Requires appropriate safety measures
• Professional laboratory use only
• Detailed safety documentation provided
• Specialized handling protocols available

Contact BIORLAB’s technical support team for detailed specifications, custom requirements, or bulk ordering information.