Higenamine

SKU 5843-65-2 Category

$30.00

CAS No.: 5843-65-2
Molecular Formula C₁₆H₁₇NO₃
Molecular Weight 271.31g/mol
Purity HPLC>98%
Chemical Family Alkaloids

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol

InChI: InChI=1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2

InChIKey: WZRCQWQRFZITDX-UHFFFAOYSA-N

Canonical SMILES: C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O

Isomeric SMILES: C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O

Synonyms: Higenamine; 5843-65-2; Demethyl-Coclaurine; Norcoclaurine; (RS)-norcoclaurine; (+-)-Norcoclaurine; (+-)-Demethylcoclaurine; DL-DEMETHYLCOCLAURINE; …

Botanical Source: Lindera aggregata(Sims) Kos-term.


Product Overview

BIORLAB presents high-purity Higenamine (norcoclaurine), a beta-adrenergic agonist with significant applications in cardiorespiratory research and metabolic studies.

Technical Specifications

  • Chemical Formula: C₁₆H₁₇NO₃
  • Source: Multiple plant species including Nandina domestica
  • Purity: ≥98% (HPLC)
  • Appearance: White to off-white powder
  • Storage: -20°C, protected from light

Key Research Applications

Primary Research Areas

  1. Cardiovascular Studies

    • β-adrenergic receptor activation
    • Heart rate modulation
    • Cardiac contractility
    • Vasodilation research
  2. Respiratory Research

    • Bronchodilation studies
    • Airway smooth muscle
    • Anti-asthmatic effects
    • Pulmonary function

Research Significance

Pharmacological Effects

  1. Cardiovascular Actions

    • Positive chronotropic effect
    • Positive inotropic effect
    • Vasodilatory properties
    • Blood pressure modulation
  2. Additional Properties

    • Lipolytic activity
    • Thermogenic effects
    • Anti-inflammatory potential
    • Metabolic enhancement

Storage & Handling

  • Store at -20°C
  • Protect from light
  • Available in research quantities
  • Stability data provided
  • Handle with appropriate PPE

Quality Assurance

  • Full spectroscopic characterization
  • Comprehensive Certificate of Analysis
  • Batch-specific HPLC profiles
  • Research-grade documentation

BIORLAB Advantage

  • Industry-leading purity
  • Consistent quality
  • Technical support
  • Custom packaging options
  • Comprehensive documentation

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.


Note: This product is intended for laboratory research purposes only. Not for human consumption.

Additional information

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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