Harpagoside

SKU 19210-12-9 Category

$40.00

CAS No.: 19210-12-9
Molecular Formula C₂₄H₃₀O₁₁
Molecular Weight 494.5g/mol
Purity HPLC>98%
Chemical Family Iridoids

Additional information

Weight

Request another packsize? Click Bulk Request.

* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: [(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate

InChI: InChI=1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1

InChIKey: KVRQGMOSZKPBNS-FMHLWDFHSA-N

Canonical SMILES: CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)OC(=O)C=CC4=CC=CC=C4

Isomeric SMILES: C[C@@]1(C[C@H]([C@]2([C@@H]1[C@@H](OC=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)OC(=O)/C=C/C4=CC=CC=C4

Synonyms: Harpagoside; 19210-12-9; E-harpagoside; UNII-8KGS1DC5ZU; 8KGS1DC5ZU; EINECS 242-881-6; CHEBI:5625; [(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate; …

Botanical Source: Scrophularia ningpoensis Hemsl.


Product Overview

Harpagoside is a bioactive iridoid glycoside naturally extracted from Devil’s Claw (Harpagophytum procumbens), renowned for its anti-inflammatory research applications. BIORLAB provides high-purity harpagoside isolated through advanced chromatographic techniques and validated analytical methods.

Technical Specifications

  • Molecular Formula: C₂₄H₃₀O₁₁
  • Molecular Weight: 494.5 g/mol
  • Appearance: White crystalline powder
  • Solubility: Soluble in methanol, ethanol, DMSO
  • Melting Point: 236-238°C

Storage and Handling

  • Store at -20°C under inert conditions
  • Protect from light and moisture
  • Stability: 2 years when properly stored
  • Solution preparation: Dissolve in DMSO
  • Avoid repeated freeze-thaw cycles

Key Research Applications

Inflammation Research

  • COX-2 inhibition studies
  • Pro-inflammatory cytokine modulation
  • NF-κB pathway investigation
  • Inflammatory mediator research

Pain Management Studies

  • Nociceptive mechanism research
  • Analgesic pathway investigation
  • Chronic pain models
  • Neural sensitivity studies

Joint Health Research

  • Cartilage protection studies
  • Osteoarthritis mechanisms
  • Joint inflammation pathways
  • Chondroprotective effects

Quality Assurance

  • HPLC purity analysis
  • Structure verified by NMR
  • Comprehensive Certificate of Analysis
  • Batch-specific documentation
  • Stringent quality control

Research Benefits

  • High biological activity
  • Excellent batch consistency
  • Suitable for in vitro/in vivo research
  • Complete technical documentation
  • Enhanced stability profile

Research Applications Highlights

  1. Anti-inflammatory Mechanisms

    • Inflammatory mediator modulation
    • COX-2 pathway studies
    • Cytokine expression research
  2. Pain Research

    • Nociceptive signaling
    • Pain pathway modulation
    • Analgesic mechanism studies
  3. Joint Health

    • Cartilage metabolism
    • Joint inflammation
    • Osteoarthritis research

Why Choose BIORLAB’s Harpagoside?

  • Industry-leading purity
  • Expert technical support
  • Comprehensive documentation
  • Competitive Pricing
  • Global shipping
  • Custom synthesis options

Technical Support

  • Method development assistance
  • Analytical documentation
  • Stability data
  • Storage recommendations
  • Application Guidance

For research use only. Not for human consumption or therapeutic use.

Additional information

Weight

BIORLAB commits to excellence and reliability.

Your orders are shipped seamlessly between countries

30 Days Warranty

You have the right to return your orders within 30 days.

Secure Payment

Your payments are secure with our private security network.

Share it :

Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

Testimonials

What Our Client Say

BIORLAB is committed to providing highly competitive natural compounds and comprehensive solutions to customers around the world.

Carol C Medical Research

Their high-quality natural products have significantly advanced our research, providing us with reliable and consistent results. BIORLAB's commitment to excellence ensures we can push the boundaries of our studies with confidence.

Chester Glass Medical Research

BIORLAB's solutions in pharmaceutical products are unparalleled. Their innovative approaches and top-notch compounds have revolutionized our development processes, making them an indispensable partner in our pursuit of groundbreaking discoveries.

Julian K Medical Research

The natural compounds from BIORLAB are always pure and effective, ensuring the highest standards in our research. Their dedication to quality and consistency sets them apart, making them our go-to source for natural pharmaceutical ingredients.

Send Your Request

You will get response in 24 hours!

Get The Report