Description
IUPAC Name: 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole
InChI: InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3
InChIKey: RERZNCLIYCABFS-UHFFFAOYSA-N
Canonical SMILES: CC1=NCCC2=C1NC3=C2C=CC(=C3)OC
Isomeric SMILES: CC1=NCCC2=C1NC3=C2C=CC(=C3)OC
Synonyms: harmaline; 304-21-2; Dihydroharmine; Harmidine; Armalin; 3,4-Dihydroharmine; Harmalol methyl ether; O-Methylharmalol; …
Botanical Source: Peganum harmala L.Seeds
Technical Specifications
- Molecular Formula: C₁₃H₁₄N₂O
- Source: Natural/synthetic
- Chemical Class: β-Carboline alkaloid
- Purity: Research grade
- Storage: -20°C, protected from light
Research Applications
Primary Research Areas
- Cancer Research
- Anti-proliferation studies against:
- HCT116 cells
- MCF7 cells
- MGC803 cells
- Cell migration inhibition
- Monoclonal formation studies
- Anti-proliferation studies against:
Key Research Properties
-
Anticancer Activity
- IC50 values (24-hour):
- HCT116: 3.84 ± 0.11 μM
- MGC803: 5.26 ± 0.46 μM
- MCF7: 8.67 ± 0.13 μM
- IC50 values (24-hour):
-
Metabolic Effects
- Glycine, serine, threonine metabolism
- Taurine and hypotaurine metabolism
- Glutathione metabolism
- Nicotinic acid/nicotinamide metabolism
Research Significance
-
Cancer Cell Lines
- Significant anti-proliferative effects
- Migration inhibition
- Colony formation suppression
- Multiple metabolic pathways
-
Metabolic Pathways
- Multiple pathway targeting
- NMR metabolomics analysis
- Comprehensive mechanism studies
- Novel N-9 modifications
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific profiles
- Research-grade documentation
Target Applications
- Cancer research centers
- Metabolic studies
- Drug development
- Academic institutions
For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.
Note: This product is intended for laboratory research purposes only.