Original price was: $1,243.00.$994.00Current price is: $994.00.
| CAS No.: | 219649-95-3 |
| Molecular Formula | C₃₆H₂₈O₁₂ |
| Molecular Weight | 652.60 g/mol |
| Purity | HPLC≥98% |
| Chemical Family | Xanthones |
| Weight |
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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.
Griffipavixanthone, a natural xanthone isolated from the fruits of Garcinia oblongifolia Champ, exhibits potent inhibitory effects on the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, with an IC50 value of 3.03 ± 0.21 μM at 48 hours. Griffipavixanthone induces cell apoptosis via the mitochondrial apoptotic pathway, accompanied by the production of reactive oxygen species (ROS). These findings highlight the potential of griffipavixanthone as a promising anti-non-small cell lung cancer agent.
IUPAC Name: (8S,8aS,12aR)-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxoxanthen-1-yl)-8,8a,10,12a-tetrahydroindeno[1,2-a]xanthen-13-one
InChI: InChI=1S/C36H28O12/c1-11-4-15-21-26(32(45)33(46)35-27(21)31(44)25-17(40)6-13(38)8-20(25)48-35)22(28(15)36(2,3)10-11)14-9-18(41)29(42)34-23(14)30(43)24-16(39)5-12(37)7-19(24)47-34/h4-9,15,22,28,37-42,45-46H,10H2,1-3H3/t15-,22-,28-/m0/s1
InChIKey: KAPVRSRPLHVWCH-JNFGOLMQSA-N
SMILES: CC1=C[C@@H]2[C@@H]([C@H](C3=C(C(=C4C(=C23)C(=O)C5=C(C=C(C=C5O4)O)O)O)O)C6=CC(=C(C7=C6C(=O)C8=C(C=C(C=C8O7)O)O)O)O)C(C1)(C)C
Synonyms: Griffipavixanthone; 219649-95-3; (8S,8aS,12aR)-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxoxanthen-1-yl)-8,8a,10,12a-tetrahydroindeno[1,2-a]xanthen-13-one; (8S,8aS,12aR)-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxoxanthen-1-yl)-8,8a,10,12a-tetrahydroindeno(1,2-a)xanthen-13-one; CHEMBL3314604; SCHEMBL18155272; GLXC-17118; rel-(+)-(8R,8aR,12aS)-8a,9,10,12a-Tetrahydro-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)indeno[1,2-a]xanthen-13(8H)-one; FLBG-1108; …
Botanical Source:
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