Description

IUPAC Name: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate

InChI: InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

InChIKey: OHCQJHSOBUTRHG-KGGHGJDLSA-N

Canonical SMILES: CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O

Isomeric SMILES: CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O

Synonyms: forskolin; Colforsin; 66575-29-9; Coleonol; colforsina; colforsine; colforsinum; Boforsin; …

Botanical Source:

Product Overview

Forskolin, a natural compound isolated from Coleus forskohlii roots, is offered by BIORLAB at research-grade purity (≥98%). This bioactive compound has gained significant research interest for its unique ability to activate adenylate cyclase and modulate various cellular processes.

Technical Specifications

• Molecular Formula: C₂₂H₃₄O₇
• Molecular Weight: 410.5 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in ethanol, DMSO; slightly soluble in water
• Purity: ≥98% (HPLC)
• Storage Temperature: -20°C

Key Research Applications

• Cell Signaling Studies

  • cAMP pathway activation
  • Enzyme regulation research
  • Signal transduction studies

• Cardiovascular Research

  • Blood pressure regulation
  • Vascular function studies
  • Heart muscle research

• Metabolic Studies

  • Weight management research
  • Cellular metabolism
  • Protein synthesis investigation

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Available in research quantities
• Stability: 24 months when properly stored

Research Significance

1. Cellular Mechanisms

   • Adenylate cyclase activation
   • cAMP level modulation
   • Enzyme pathway regulation

2. Cardiovascular Effects

   • Blood vessel relaxation
   • Heart muscle function
   • Blood pressure modulation

3. Therapeutic Potential

   • Glaucoma research
   • Asthma studies
   • Weight management investigation

Quality Assurance

• Full spectroscopic data provided
• Comprehensive Certificate of Analysis
• Batch-specific chromatographic profile
• Research-grade documentation

Application Areas

1. Pharmaceutical Research

   • Drug development studies
   • Mechanism investigations
   • Formulation research

2. Clinical Studies Support

   • Standardization
   • Method development
   • Reference material

Safety Considerations

• Research use only
• May affect the heart rate
• Monitor blood pressure during research
• Proper PPE required

Additional Features

• Batch-to-batch consistency
• Method validation support
• Technical consultation
• Research collaboration potential

For detailed technical information or custom requirements, contact BIORLAB’s scientific team.

Note: This product is intended for laboratory research purposes only. Not for human consumption or therapeutic use without proper approval.