Description
IUPAC Name: (1R,4R,5R,7R,8R,11R,13S,17S,18S,19R)-4,5,7,8,17-pentahydroxy-14,18-dimethyl-6-methylidene-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-ene-9,16-dione
InChI: InChI=1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1
InChIKey: UCUWZJWAQQRCOR-OKNZMGBLSA-N
Canonical SMILES: CC1=CC(=O)C(C2(C1CC3C45C2C(C(C(=C)C4(C(C(=O)O3)O)O)O)(OC5)O)C)O
Isomeric SMILES: CC1=CC(=O)[C@H]([C@]2([C@H]1C[C@@H]3[C@]45[C@@H]2[C@]([C@@H](C(=C)[C@@]4([C@H](C(=O)O3)O)O)O)(OC5)O)C)O
Synonyms: Eurycomanone; 84633-29-4; Pasakbumin-A; X7F43HL2HB; pasakbumin A; (1R,4R,5R,7R,8R,11R,13S,17S,18S,19R)-4,5,7,8,17-pentahydroxy-14,18-dimethyl-6-methylidene-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-ene-9,16-dione; 4,5,7,8,17-Pentahydroxy-14,18-dimethyl-6-methylidene-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-ene-9,16-dione; NSC-339187; …
Botanical Source: Tongkat Ali
Product Overview
BIORLAB presents high-purity Eurycomanone, a key bioactive compound from Tongkat Ali (Eurycoma longifolia) with significant applications in cancer research and metabolic studies.
Key Research Applications
Primary Research Areas
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Cancer Research
- Cell proliferation inhibition
- Migration inhibition
- Invasion studies
- Apoptosis induction
-
Molecular Studies
- GRP78 expression
- mRNA stability
- Transcription regulation
- Cell signaling
Research Significance
Biological Activities
-
Anti-cancer Effects
- Downregulates GRP78
- Inhibits cell proliferation
- Reduces migration
- Induces apoptosis
-
Enhanced Effects
- Increases TSA sensitivity
- Multiple cancer-type inhibition
- Transcriptional control
- Cellular regulation
Molecular Mechanisms
Mode of Action
- Primary Effects
- GRP78 mRNA stability reduction
- Transcription inhibition
- Cell growth suppression
- Metastasis prevention
Storage & Handling
- Store at -20°C
- Protect from light
- Available in research quantities
- Stability data provided
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific HPLC profiles
- Research-grade documentation
For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.
Note: This product is intended for laboratory research purposes only.