Description

IUPAC Name: 6,7-dihydroxychromen-2-one

InChI: InChI=1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H

InChIKey: ILEDWLMCKZNDJK-UHFFFAOYSA-N

Canonical SMILES: C1=CC(=O)OC2=CC(=C(C=C21)O)O

Isomeric SMILES: C1=CC(=O)OC2=CC(=C(C=C21)O)O

Synonyms: Esculetin; 305-01-1; 6,7-DIHYDROXYCOUMARIN; Aesculetin; 6,7-Dihydroxy-2H-chromen-2-one; Cichorigenin; Esculetol; Cichoriin aglucon; …

Botanical Source: Euphorbia lathyris L

Product Overview

High-purity Esculetin (6,7-dihydroxychromen-2-one), a natural coumarin isolated from various plant sources, is manufactured to exceptional standards for pharmaceutical research and biological studies.

Technical Specifications

• Molecular Formula: C₉H₆O₄
• Molecular Weight: 178.14 g/mol
• Purity: ≥98% (HPLC)
• Appearance: Off-white to pale yellow crystalline powder
• Solubility: Soluble in DMSO, methanol; sparingly soluble in water

Key Features & Benefits

• Natural coumarin compound
• Strong fluorescence properties
• Validated structure and activity
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization

Research Applications

1. Biochemical Research

   • Antioxidant studies
   • ROS modulation research
   • Enzyme inhibition studies
   • Metal chelation investigations

2. Pharmaceutical Development

   • Anti-inflammatory research
   • Neuroprotection studies
   • Cancer cell investigations
   • Drug discovery screening

3. Cell Biology Studies

   • Cell signaling pathways
   • Apoptosis mechanisms
   • Oxidative stress research
   • Cellular protection studies

Storage & Handling

• Store at -20°C
• Protect from light
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Fluorescence protocols

Key Research Areas

1. Oxidative Stress

   • Free radical scavenging
   • Antioxidant mechanisms
   • Cellular protection studies
   • ROS/RNS modulation

2. Cell Death Pathways

   • Apoptosis mechanisms
   • Cell survival studies
   • Mitochondrial function
   • Signal transduction

3. Anti-inflammatory Effects

   • Cytokine modulation
   • NF-κB pathway studies
   • COX/LOX inhibition
   • Inflammatory mediators

This premium-grade Esculetin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]