Description

High-purity Dioscin, a natural steroidal saponin isolated from Dioscorea species, is manufactured to exceptional standards for pharmaceutical research and drug development.

Technical Specifications

• Molecular Formula: C₄₅H₇₂O₁₆
• Molecular Weight: 869.0 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO, and methanol; poorly soluble in water

IUPAC Name: (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5’R,6R,7S,8R,9S,12S,13R,16S)-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2′-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol

InChI: InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1

InChIKey: VNONINPVFQTJOC-ZGXDEBHDSA-N

Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1

Isomeric SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)C)C)OC1

Synonyms: Dioscin; 19057-60-4; Collettiside III; Dioscine; CCRIS 4123; CHEBI:74023; UNII-3B95U4OLWV; 3B95U4OLWV; …

Botanical Source: Dioscoreae Nipponicae Rhizoma

Key Features & Benefits

• Natural steroidal saponin
• Potent anti-cancer properties
• Anti-inflammatory activity
• Hepatoprotective effects
• Comprehensive Certificate of Analysis

Research Applications

1. Cancer Research

   • Anti-tumor studies
   • Apoptosis mechanisms
   • Cell cycle regulation
   • Metastasis inhibition

2. Pharmaceutical Development

   • Anti-inflammatory studies
   • Hepatoprotection research
   • Cardiovascular studies
   • Drug discovery screening

3. Mechanism Studies

   • Cell signaling pathways
   • Molecular target identification
   • Structure-activity relationships
   • Pharmacokinetic investigations

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Cancer Biology

   • Tumor suppression
   • Apoptosis induction
   • Anti-metastatic effects
   • Drug resistance studies

2. Liver Protection

   • Hepatotoxicity prevention
   • Liver fibrosis research
   • Metabolic regulation
   • Oxidative stress studies

3. Cardiovascular Research

   • Cardioprotection studies
   • Vascular function
   • Atherosclerosis research
   • Inflammation modulation

This premium-grade Dioscin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]