Description
High-purity Demethoxycurcumin, a natural curcuminoid from Curcuma longa with demonstrated anti-inflammatory, antioxidant, and anti-cancer properties. Second most abundant curcuminoid after curcumin in turmeric.
Technical Specifications
- Molecular Formula: C₂₀H₁₈O₅
- Molecular Weight: 338.4 g/mol
- Purity: ≥98% (HPLC)
- Appearance: Orange-yellow crystalline powder
- Solubility: Soluble in DMSO, ethanol; poorly soluble in water
IUPAC Name: (1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
InChI: InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+
InChIKey: HJTVQHVGMGKONQ-LUZURFALSA-N
Canonical SMILES: COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC=C(C=C2)O)O
Isomeric SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O
Synonyms: Demethoxycurcumin; 22608-11-3; 24939-17-1; monodemethoxycurcumin; curcumin II; BHCFM; desmethoxycurcumin; Demethoxy Curcumin; …
Botanical Source: Zingiber officinale Rose.
Key Features & Benefits
- Natural curcuminoid
- Enhanced stability compared to curcumin
- Superior biological activity
- Validated structure and purity
- Comprehensive Certificate of Analysis
Research Applications
-
Cancer Research
- Anti-proliferative studies
- Apoptosis induction
- Cell cycle regulation
- Metastasis inhibition
-
Inflammatory Studies
- NF-κB pathway modulation
- Cytokine regulation
- COX-2 inhibition
- Anti-inflammatory mechanisms
-
Oxidative Stress Research
- Free radical scavenging
- Antioxidant mechanisms
- Cellular protection
- ROS modulation
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Package Sizes
- 5mg
- 10mg
- 25mg
- 50mg
- Bulk quantities available
Key Research Areas
-
Molecular Mechanisms
- Signal transduction
- Gene expression
- Protein interactions
- Enzyme inhibition
-
Therapeutic Applications
- Anti-cancer strategies
- Anti-inflammatory therapy
- Antioxidant development
- Drug discovery
Biological Activities
- Anti-proliferative effects
- Pro-apoptotic activity
- Anti-inflammatory properties
- Antioxidant capacity
Comparative Advantages
- Better stability than curcumin
- Enhanced bioavailability
- Specific molecular targeting
- Reduced degradation
This premium-grade Demethoxycurcumin is designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.
For research and development purposes only. Not for human consumption or clinical use.