Cytisine

SKU 485-35-8 Category

$30.00

CAS No.: 485-35-8
Molecular Formula C₁₁H₁₄N₂O
Molecular Weight 190.24g/mol
Purity HPLC>98%
Chemical Family Alkaloids

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one

InChI: InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1

InChIKey: ANJTVLIZGCUXLD-DTWKUNHWSA-N

Canonical SMILES: C1C2CNCC1C3=CC=CC(=O)N3C2

Isomeric SMILES: C1[C@H]2CNC[C@@H]1C3=CC=CC(=O)N3C2

Synonyms: CYTISINE; 485-35-8; Baptitoxine; Sophorine; Cytisinicline; Baptitoxin; Laburnin; Cytiton; …

Botanical Source: Thermopsis lanceolata R.Br.


Product Overview

Cytisine, a plant-derived alkaloid primarily from Cytisus laburnum, is provided by BIORLAB at pharmaceutical-grade purity (≥98%). This compound is significant for smoking cessation research and nicotinic acetylcholine receptor studies.

Technical Specifications

  • Molecular Formula: C₁₁H₁₄N₂O
  • Molecular Weight: 190.24 g/mol
  • Appearance: White crystalline powder
  • Solubility: Soluble in water
  • Peak Concentration: 2 hours post-dose
  • Half-life: 4.8 hours

Key Research Applications

  • Smoking Cessation Studies

    • Nicotinic receptor research
    • Addiction mechanisms
    • Behavioral studies
  • Drug Development

    • Bioavailability studies
    • Formulation research
    • Safety evaluations

Mechanism of Action

  • Partial agonist of α4β2 nicotinic receptors
  • Mimics nicotine effects
  • Excreted unchanged renally
  • Low drug interaction risk

Clinical Research Significance

  1. Efficacy Data

    • 59% higher abstinence rate vs placebo
    • NNT: 6.35
    • Higher abstinence vs nicotine replacement
  2. Safety Profile

    • Used since the 1960s in Eastern Europe
    • Self-limiting adverse effects
    • Primarily gastrointestinal effects

Quality Assurance

  • Full spectroscopic data
  • Certificate of Analysis
  • Batch-specific testing
  • Research-grade documentation

Storage & Handling

  • Store at a controlled temperature
  • Protect from light and moisture
  • Available in research quantities
  • Stability data provided

Technical Support

  • Method development assistance
  • Analytical testing guidance
  • Research protocol support
  • Documentation assistance

For detailed technical information or custom requirements, contact BIORLAB’s scientific team.


Note: This product is intended for laboratory research purposes only. Not for human consumption or therapeutic use without proper approval.

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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