Description
IUPAC Name: (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
InChI: InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1
InChIKey: ANJTVLIZGCUXLD-DTWKUNHWSA-N
Canonical SMILES: C1C2CNCC1C3=CC=CC(=O)N3C2
Isomeric SMILES: C1[C@H]2CNC[C@@H]1C3=CC=CC(=O)N3C2
Synonyms: CYTISINE; 485-35-8; Baptitoxine; Sophorine; Cytisinicline; Baptitoxin; Laburnin; Cytiton; …
Botanical Source: Thermopsis lanceolata R.Br.
Product Overview
Cytisine, a plant-derived alkaloid primarily from Cytisus laburnum, is provided by BIORLAB at pharmaceutical-grade purity (≥98%). This compound is significant for smoking cessation research and nicotinic acetylcholine receptor studies.
Technical Specifications
- Molecular Formula: C₁₁H₁₄N₂O
- Molecular Weight: 190.24 g/mol
- Appearance: White crystalline powder
- Solubility: Soluble in water
- Peak Concentration: 2 hours post-dose
- Half-life: 4.8 hours
Key Research Applications
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Smoking Cessation Studies
- Nicotinic receptor research
- Addiction mechanisms
- Behavioral studies
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Drug Development
- Bioavailability studies
- Formulation research
- Safety evaluations
Mechanism of Action
- Partial agonist of α4β2 nicotinic receptors
- Mimics nicotine effects
- Excreted unchanged renally
- Low drug interaction risk
Clinical Research Significance
-
Efficacy Data
- 59% higher abstinence rate vs placebo
- NNT: 6.35
- Higher abstinence vs nicotine replacement
-
Safety Profile
- Used since the 1960s in Eastern Europe
- Self-limiting adverse effects
- Primarily gastrointestinal effects
Quality Assurance
- Full spectroscopic data
- Certificate of Analysis
- Batch-specific testing
- Research-grade documentation
Storage & Handling
- Store at a controlled temperature
- Protect from light and moisture
- Available in research quantities
- Stability data provided
Technical Support
- Method development assistance
- Analytical testing guidance
- Research protocol support
- Documentation assistance
For detailed technical information or custom requirements, contact BIORLAB’s scientific team.
Note: This product is intended for laboratory research purposes only. Not for human consumption or therapeutic use without proper approval.