Description
IUPAC Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
InChI: InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChIKey: PMATZTZNYRCHOR-CGLBZJNRSA-N
Canonical SMILES: CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Isomeric SMILES: CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
Synonyms: cyclosporin A; cyclosporine; Ciclosporin; Cyclosporin; 59865-13-3; Sandimmune; Cyclosporine A; Neoral; …
Botanical Source:
Product Overview
BIORLAB provides high-purity Cyclosporin A (CsA), a selective immunosuppressant with significant applications in immunology research, transplantation studies, and inflammatory disease research.
Technical Specifications
- Molecular Weight: 1202.61 g/mol
- Appearance: White crystalline powder
- Purity: ≥98% (HPLC)
- Solubility: DMSO, ethanol, methanol
- Storage: -20°C, protected from light
- Application: Research grade
Research Applications
Primary Research Areas
- Immunosuppression studies
- Transplantation research
- Recurrent abortion studies
- Inflammatory disease research
Key Mechanisms
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Immunological Studies
- T-cell inhibition
- Lymphocyte suppression
- Maternal-fetal immune tolerance
- Inflammatory modulation
-
Clinical Research Applications
- Transplant rejection prevention
- Recurrent spontaneous abortion
- Autoimmune conditions
- Inflammatory disorders
Research Significance
-
Therapeutic Potential
- Selective immunosuppression
- Reversible inhibition
- Specific lymphocyte targeting
- Immune tolerance modulation
-
Biological Activities
- Calcineurin inhibition
- T-cell regulation
- Cytokine modulation
- Inflammatory control
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw
- Special handling protocols required
- Stability data provided
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific HPLC profiles
- Stability testing data
- Research-grade documentation
Research Applications
Immunology Research
- T-cell function studies
- Transplantation models
- Autoimmune Research
- Inflammatory studies
Reproductive Research
- Recurrent abortion studies
- Maternal-fetal tolerance
- Implantation research
- Pregnancy outcomes
Technical Support Features
- Method development assistance
- Analytical testing guidance
- Stability data available
- Research protocol support
- Documentation assistance
For detailed technical information or custom requirements, contact BIORLAB’s scientific team.
Note: This product is for research use only. Not for human use.