Description

IUPAC Name: (1R,2S,6R,7S)-2,6-dimethyl-4,10-dioxatricyclo[5.2.1.02,6]decane-3,5-dione

InChI: InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-

InChIKey: DHZBEENLJMYSHQ-XCVPVQRUSA-N

Canonical SMILES: CC12C3CCC(C1(C(=O)OC2=O)C)O3

Isomeric SMILES: C[C@@]12[C@H]3CC[C@@H]([C@@]1(C(=O)OC2=O)C)O3

Synonyms: cantharidin; Cantharone; CANTHARIDINE; 56-25-7; Kantaridin; Cantharides camphor; Kantharidin; 1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride; …

Botanical Source: Lytta vesicatoria

Product Overview

Cantharidin, a potent terpenoid isolated from blister beetles, is provided by BIORLAB at research-grade purity (≥98%). This compound has garnered significant research interest for its anticancer properties and protein phosphatase inhibition studies.

Technical Specifications

• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2 g/mol
• Appearance: White crystalline powder
• Solubility: Soluble in chloroform, and acetone; slightly soluble in ethanol
• Purity: ≥98% (HPLC)
• Melting Point: 217-218°C

Key Research Applications

• Cancer Research
  • PP1 and PP2A inhibition studies
  • Cell cycle regulation
  • Apoptosis pathway investigation
• Drug Development
  • Anticancer agent research
  • Novel analogue development
  • Structure-activity relationships

Mechanism of Action

• Selective inhibition of PP1 and PP2A
• Induction of apoptosis
• Cell cycle modulation
• Anti-inflammatory effects

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Handle with extreme caution
• Proper PPE required

Research Significance

1. Anticancer Properties

   • Induces cancer cell apoptosis
   • Inhibits cell invasion and metastasis
   • Enhances immunity

2. Molecular Mechanisms

   • Protein phosphatase inhibition
   • Cell cycle regulation
   • Multiple pathway modulation

Quality Assurance

• Complete analytical documentation
• Comprehensive Certificate of Analysis
• Batch-specific purity data
• Research-grade validation

Safety Considerations

• Highly toxic compound
• Requires controlled environment
• Strict safety protocols needed
• Special disposal procedures

Research Focus Areas

• Cancer Biology

  • Cell death mechanisms
  • Signal transduction
  • Drug resistance studies

• Drug Development

  • Novel formulations
  • Analogue synthesis
  • Delivery systems

Application Areas

1. Pharmaceutical Research

   • Anticancer drug development
   • Mechanism studies
   • Combination therapy research

2. Clinical Studies Support

   • Reference standards
   • Method validation
   • Analytical testing

Important Research Notes

• Potent vesicant properties
• Strict concentration control required
• Careful handling essential
• Not for direct therapeutic use

For detailed technical information or custom requirements, contact BIORLAB’s scientific team.

WARNING: This compound is highly toxic and for research and development purposes only. Requires specialized handling and safety protocols. Not for human use.