Camptothecin

SKU 7689-03-4 Category

$30.00

CAS No.: 7689-03-4
Molecular Formula C₂₀H₁₆N₂O₄
Molecular Weight 348.4g/mol
Purity HPLC>98%
Chemical Family Alkaloids

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

InChI: InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1

InChIKey: VSJKWCGYPAHWDS-FQEVSTJZSA-N

Canonical SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O

Isomeric SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O

Synonyms: camptothecin; 7689-03-4; Camptothecine; (S)-(+)-Camptothecin; Campathecin; (+)-Camptothecin; (+)-Camptothecine; d-Camptothecin; …

Botanical Source: Camptotheca acuminata.


Product Overview

BIORLAB provides high-purity Camptothecin (≥98%), a potent topoisomerase I inhibitor isolated from Camptotheca acuminata. This compound is crucial for cancer research and DNA topology studies.

Technical Specifications

  • Molecular Formula: C₂₀H₁₆N₂O₄
  • Molecular Weight: 348.4 g/mol
  • Appearance: Pale yellow crystalline powder
  • Purity: ≥98% (HPLC)
  • Melting Point: 264-267°C
  • Solubility: DMSO, DMF
  • Storage: -20°C, protected from light

Research Applications

Cancer Research

  • TOP1 inhibition studies
  • DNA damage research
  • Apoptosis mechanisms
  • Cell cycle studies

Key Research Areas

  1. Molecular Studies

    • DNA topology research
    • Cell death pathways
    • Drug resistance mechanisms
    • Combination therapy studies
  2. Drug Development

    • Analog synthesis
    • Structure-activity relationships
    • Delivery systems
    • Formulation research

Research Significance

  1. Therapeutic Potential

    • Anticancer activity
    • TOP1 targeting
    • DNA damage induction
    • Cell cycle arrest
  2. Biological Activities

    • S-phase specific
    • DNA cleavage
    • Apoptosis induction
    • Growth inhibition

Safety Considerations

  • Highly potent compound
  • Cytotoxic agent
  • Requires proper containment
  • Special disposal procedures

Storage & Handling

  • Store at -20°C
  • Protect from light
  • Available in research quantities
  • Stability data provided
  • Special handling protocols required

Quality Assurance

  • Full spectroscopic characterization
  • Comprehensive Certificate of Analysis
  • Batch-specific HPLC profiles
  • Stability testing data
  • Research-grade documentation

Product Features & Benefits

  • Highest available purity
  • Batch-to-batch consistency
  • Comprehensive documentation
  • Technical support available
  • Custom packaging options

Target Applications

  • Cancer research centers
  • Drug development facilities
  • Pharmaceutical R&D laboratories
  • Academic research institutions

Technical Support Features

  • Method development assistance
  • Analytical testing guidance
  • Stability data available
  • Research protocol support
  • Documentation assistance

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.


WARNING: This compound is highly potent and cytotoxic. Handle with appropriate safety measures.

Additional information

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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