Description
IUPAC Name: (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
InChI: InChI=1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+
InChIKey: AYMYWHCQALZEGT-ORCRQEGFSA-N
Canonical SMILES: C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O
Isomeric SMILES: C1=CC(=C(C=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O)O
Synonyms: butein; 487-52-5; 2′,3,4,4′-Tetrahydroxychalcone; 2′,4′,3,4-Tetrahydroxychalcone; 3,4,2′,4′-Tetrahydroxychalcone; AC1NQY7L; (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; UNII-4WVS5M0LGF; …
Botanical Source:
Product Overview
High-purity Butein (2′,3,4,4′-Tetrahydroxychalcone), a natural chalcone flavonoid isolated from various plant sources including Rhus verniciflua, manufactured to exceptional standards for pharmaceutical research and biological studies.
Technical Specifications
- Molecular Formula: C₁₅H₁₂O₅
- Molecular Weight: 272.25 g/mol
- Purity: ≥98% (HPLC)
- Appearance: Yellow crystalline powder
- Solubility: Soluble in DMSO, ethanol; sparingly soluble in water
Key Features & Benefits
- Natural chalcone compound
- Advanced purification technology
- Validated structure and activity
- Comprehensive Certificate of Analysis
- Full spectroscopic characterization
Research Applications
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Cancer Research
- Anti-proliferative studies
- Apoptosis induction research
- Cell cycle regulation
- Angiogenesis studies
-
Pharmaceutical Development
- Anti-inflammatory research
- Antioxidant studies
- Signal transduction research
- Drug discovery screening
-
Mechanism Studies
- Cell signaling pathways
- Molecular target identification
- Enzyme inhibition studies
- ROS modulation research
Storage & Handling
- Store at -20°C
- Protect from light and moisture
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Research Support
BIORLAB provides:
- Technical consultation
- Analytical method support
- Stability data
- Custom synthesis options
- Application Guidance
Key Research Areas
-
Anticancer Mechanisms
- Cell death pathways
- Cancer cell metabolism
- Metastasis inhibition
- Drug resistance studies
-
Anti-inflammatory Effects
- Cytokine modulation
- NF-κB pathway studies
- COX-2 inhibition research
- Inflammatory mediators
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Antioxidant Properties
- Free radical scavenging
- Oxidative stress protection
- Cellular defense mechanisms
This premium-grade Butein is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.
For research and development purposes only. Not for human consumption or clinical use.
[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]