Description
IUPAC Name: (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
InChI: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
InChIKey: IYGYMKDQCDOMRE-ZWKOTPCHSA-N
Canonical SMILES: CN1CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Isomeric SMILES: CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Synonyms: bicuculline; (+)-Bicuculline; 485-49-4; d-Bicuculline; Bicculine; Bicucullin; Bicuculline (+); CHEBI:3092; …
Botanical Source: Corydalis decumbens (Thunb.) Pers.
SAFETY WARNING
RESTRICTED COMPOUND – High potency competitive GABA antagonist requiring special handling and safety protocols. For authorized research facilities only.
Product Overview
BIORLAB provides high-purity Bicuculline for authorized neuroscience research facilities. Requires strict safety protocols and specialized handling.
Technical Specifications
- Molecular Formula: C₂₀H₁₇NO₆
- Source: Semi-synthetic
- Appearance: White crystalline powder
- Purity: ≥98% (HPLC)
- Storage: -20°C, desiccated
RESTRICTED USE
- Licensed facilities only
- Specialized safety protocols required
- Documentation mandatory
- Training requirements enforced
Research Applications
Authorized research only under strict protocols
Primary Research Areas
- GABA receptor studies
- Neurotransmission research
- Epilepsy models
- Neuropharmacology
Pharmacological Properties
- Selective GABA-A antagonist
- Competitive inhibition
- Convulsant activity
- Rapid onset
Safety Requirements
- Full PPE mandatory
- Containment protocols
- Emergency procedures
- Medical supervision
- Antidote availability
Storage & Security
- Controlled substance protocols
- Secure -20°C storage
- Access Restrictions
- Documentation required
- Chain of custody protocols
Documentation Required
- Research authorization
- Facility certification
- Personnel training records
- Usage documentation
- Safety protocols
- Disposal procedures
For authorized facilities only. Contact BIORLAB’s compliance team for licensing requirements.
WARNING: Potent neurotoxin. Authorized research facilities only.