Original price was: $25.00.$20.00Current price is: $20.00.
| CAS No.: | 19879-30-2 |
| Molecular Formula | C₂₁H₂₂O₄ |
| Molecular Weight | 338.40 g/mol |
| Purity | HPLC≥98% |
| Chemical Family | Flavonoids |
| Weight |
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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.
Bavachinin, a natural compound isolated from the Chinese herb Fructus Psoraleae, exhibits potent anti-angiogenic activity both in vitro and in vivo. Bavachinin inhibits the increase in HIF-1α activity in human KB carcinoma (a HeLa cell derivative) and human HOS osteosarcoma cells under hypoxia in a concentration-dependent manner, likely by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1α. Bavachinin significantly suppresses Th2 cytokine production, including IL-4, IL-5, and IL-13. Notably, Bavachinin almost completely blocks inflammation in the ovalbumin (OVA)-sensitized animal asthma model.
IUPAC Name: (2S)-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
InChI: InChI=1S/C21H22O4/c1-13(2)4-5-15-10-17-18(23)11-20(14-6-8-16(22)9-7-14)25-21(17)12-19(15)24-3/h4,6-10,12,20,22H,5,11H2,1-3H3/t20-/m0/s1
InChIKey: VOCGSQHKPZSIKB-FQEVSTJZSA-N
SMILES: CC(=CCC1=CC2=C(C=C1OC)O[C@@H](CC2=O)C3=CC=C(C=C3)O)C
Synonyms: Bavachinin; 19879-30-2; Bavachinin A; 7-O-Methylbavachin; VL3EV483SZ; 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-, (2S)-; UNII-VL3EV483SZ; BRN 3629340; …
Botanical Source: Psoralea Fruit (Psoralea corylifolia)
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