Description
Aucubin, an iridoid glycoside, exhibits a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic, and anti-tumor properties. Aucubin is considered a potential therapeutic option for osteoarthritis (OA) due to its anti-inflammatory and chondroprotective effects. In rat models of sciatic nerve injury, Aucubin administration enhanced nerve regeneration, indicating its potential as a therapeutic compound for the human peripheral nervous system following various nerve injuries. Additionally, Aucubin may mitigate obesity-induced atherosclerosis by attenuating TNF-α-mediated inflammatory responses.
IUPAC Name: (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
InChI: InChI=1S/C15H22O9/c16-4-6-3-8(18)7-1-2-22-14(10(6)7)24-15-13(21)12(20)11(19)9(5-17)23-15/h1-3,7-21H,4-5H2/t7-,8+,9+,10+,11+,12-,13+,14-,15-/m0/s1
InChIKey: RJWJHRPNHPHBRN-FKVJWERZSA-N
SMILES: C1=CO[C@H]([C@H]2[C@@H]1[C@@H](C=C2CO)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
Synonyms: Aucubin; 479-98-1; Aucuboside; rhinanthin; UNII-2G52GS8UML; EINECS 207-540-8; 2G52GS8UML; NSC 407293; …
Botanical Source: Aucuba chinensis