Description

IUPAC Name: (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

InChI: InChI=1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

InChIKey: QMNWISYXSJWHRY-YLNUDOOFSA-N

Canonical SMILES: CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)O)C

Isomeric SMILES: C[C@]12CC[C@@]34C[C@@]35CC[C@@H](C([C@@H]5[C@H](C[C@H]4[C@@]1(C[C@@H]([C@@H]2[C@]6(CC[C@H](O6)C(C)(C)O)C)O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)(C)C)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O

Synonyms: Astragaloside IV; 84687-43-4; Cyclosiversioside F; 1J6XA9YCFV; CHEBI:65457; Astrasieversianin XIV; (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; (2R,3R,4S,5S,6R)-2-[[(1S,3R,8R,9S,11S,12S,14S,15R,16R)-14-Hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; …

Botanical Source: Astragali radix

Product Overview

High-purity Astragaloside IV, a bioactive saponin isolated from Astragalus membranaceus (Huangqi), is manufactured to exceptional standards for pharmaceutical research and therapeutic development applications.

Technical Specifications

• Molecular Formula: C₄₁H₆₈O₁₄
• Molecular Weight: 785 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO, methanol; sparingly soluble in water

Key Features & Benefits

• Natural cycloartane glycoside
• Advanced purification technology
• Validated chemical structure
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization

Research Applications

1. Cardiovascular Research

   • Cardioprotective mechanisms
   • Vascular function studies
   • Endothelial cell research
   • Heart failure investigations

2. Pharmaceutical Development

   • Anti-inflammatory studies
   • Antifibrotic research
   • Kidney function investigations
   • Immunomodulation studies

3. Cell Biology Research

   • Cell signaling pathways
   • Telomerase activation studies
   • Cellular aging research
   • Oxidative stress protection

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Avoid repeated freeze-thaw cycles
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Full analytical documentation
• Traceable lot numbers
• Stability monitoring data

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Cardiovascular Protection

   • Myocardial protection
   • Vascular endothelial function
   • Cardiac remodeling studies
   • Blood pressure regulation

2. Kidney Function

   • Nephroprotective mechanisms
   • Diabetic nephropathy research
   • Renal fibrosis studies

3. Anti-aging Research

   • Telomerase activation
   • Cellular senescence
   • Oxidative stress protection

This premium-grade Astragaloside IV is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.