Description

IUPAC Name: (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

InChI: InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1

InChIKey: JXSVIVRDWWRQRT-UYDOISQJSA-N

Canonical SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)O

Isomeric SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O

Synonyms: Asiatic acid; 464-92-6; Dammarolic acid; NSC 166063; UNII-9PA5A687X5; CHEBI:2873; HSDB 7662; 9PA5A687X5; …

Botanical Source: Centella asiatica （L.）Urb.

Product Overview

BIORLAB presents high-purity Asiatic Acid (AA), a pentacyclic triterpene derived from Centella Asiatica with significant applications in cancer research, cardiovascular protection, and anti-inflammatory studies.

Technical Specifications

• Molecular C₃₀H₄₈O₅
• Source: Centella asiatica
• Purity: ≥98% (HPLC)
• Appearance: White crystalline powder

Key Research Applications

Cancer Research

1. Anti-tumor Properties
   • Proliferation inhibition
   • Apoptosis induction
   • Invasion/metastasis inhibition
   • Cell autophagy regulation

Cardiovascular Research

1. Cardioprotective Effects
   • DOX-induced cardiotoxicity protection
   • Iron export promotion
   • Ferroptosis inhibition
   • Nrf2-dependent mechanisms

Research Significance

Biological Activities

1. Cancer Cell Effects

   • Cell proliferation control
   • Apoptosis pathway activation
   • Metastasis inhibition
   • Drug resistance modulation

2. Cardioprotective Mechanisms

   • FPN-mediated iron export
   • Cardiac function preservation
   • Cardiomyocyte protection
   • Nrf2 pathway activation

Storage & Handling

• Store at -20°C
• Protect from light and moisture
• Available in research quantities
• Stability data provided

Quality Assurance

• Full spectroscopic characterization
• Comprehensive Certificate of Analysis
• Batch-specific HPLC profiles
• Research-grade documentation

BIORLAB Advantage

• Industry-leading purity
• Consistent quality
• Technical support
• Custom packaging options

For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.

Note: This product is intended for laboratory research purposes only.