Description
IUPAC Name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
InChIKey: BJRNKVDFDLYUGJ-RMPHRYRLSA-N
Canonical SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O
Isomeric SMILES: C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
Synonyms: arbutin; 497-76-7; Arbutoside; Ursin; Uvasol; beta-Arbutin; p-Arbutin; 4-Hydroxyphenyl beta-D-glucopyranoside; …
Botanical Source: Bergenia purpurascens
Arbutin is a naturally occurring hydroquinone glycoside extensively used in pharmaceutical research and cosmetic development. BIORLAB offers high-purity arbutin isolated from natural sources, meeting stringent quality standards for research and development applications.
Technical Specifications
- CAS Number: 497-76-7
- Molecular Formula: C₁₂H₁₆O₇
- Purity: ≥98% (HPLC)
- Appearance: White crystalline powder
- Molecular Weight: 272.25 g/mol
- Melting Point: 199-201°C
- Solubility: Readily soluble in water, partially soluble in methanol
- pH Value: 5.0-7.0 (1% aqueous solution)
- Optical Rotation: -62° to -66° (c=1.0, H2O)
Storage and Handling Requirements
- Store at 2-8°C in airtight containers
- Protect from light and moisture
- Avoid exposure to high temperatures
- Stable for 24 months when properly stored
- Hygroscopic nature requires careful handling
Key Research Applications
-
Pharmaceutical Research:
- Skin-lightening mechanisms
- Melanin synthesis inhibition studies
- Tyrosinase inhibition research
- Safety and efficacy evaluations
-
Cosmetic Development:
- Skin brightening formulations
- Anti-hyperpigmentation studies
- Natural cosmetic ingredient research
- Stability testing in various formulations
-
Biochemical Studies:
- Enzyme inhibition mechanisms
- Cell culture investigations
- Bioavailability studies
- Structure-activity relationship analysis
Biological Properties
- Natural tyrosinase inhibitor
- Melanin synthesis regulation
- Antioxidant activity
- Non-cytotoxic at recommended concentrations
- Superior stability compared to hydroquinone
Quality Assurance
- Manufactured under GMP guidelines
- Full Certificate of Analysis provided
- Comprehensive analytical documentation
- Batch-specific purity testing
- Endotoxin and microbial testing are available
Research Areas
Ideal for studies in:
- Dermatological research
- Cosmetic science
- Cell Biology
- Pharmaceutical development
- Natural product chemistry
Added Value Features
- Research-grade purity
- Full technical documentation
- Method development support
- Stability data available
- Custom synthesis capabilities
Target Industries
- Pharmaceutical R&D
- Cosmetic development
- Academic research
- Biotechnology
- Contract research organizations
Regulatory Information
- Meets USP/EP specifications
- Suitable for research and development
- Available with full regulatory documentation
- Compliant with international quality standards
For research and development purposes only. Not for human consumption or direct cosmetic application.