Arbutin

SKU 497-76-7 Category

$20.00

CAS No.: 497-76-7
Molecular Formula C₁₂H₁₆O₇
Molecular Weight 272.25g/mol
Purity HPLC>98%
Chemical Family Phenols

Additional information

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* Warning: BIORLAB’s Natural Compounds are for laboratory research purposes only.

Description


 

IUPAC Name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol

InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1

InChIKey: BJRNKVDFDLYUGJ-RMPHRYRLSA-N

Canonical SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O

Isomeric SMILES: C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O

Synonyms: arbutin; 497-76-7; Arbutoside; Ursin; Uvasol; beta-Arbutin; p-Arbutin; 4-Hydroxyphenyl beta-D-glucopyranoside; …

Botanical Source: Bergenia purpurascens


 

Arbutin is a naturally occurring hydroquinone glycoside extensively used in pharmaceutical research and cosmetic development. BIORLAB offers high-purity arbutin isolated from natural sources, meeting stringent quality standards for research and development applications.

Technical Specifications

  • CAS Number: 497-76-7
  • Molecular Formula: C₁₂H₁₆O₇
  • Purity: ≥98% (HPLC)
  • Appearance: White crystalline powder
  • Molecular Weight: 272.25 g/mol
  • Melting Point: 199-201°C
  • Solubility: Readily soluble in water, partially soluble in methanol
  • pH Value: 5.0-7.0 (1% aqueous solution)
  • Optical Rotation: -62° to -66° (c=1.0, H2O)

Storage and Handling Requirements

  • Store at 2-8°C in airtight containers
  • Protect from light and moisture
  • Avoid exposure to high temperatures
  • Stable for 24 months when properly stored
  • Hygroscopic nature requires careful handling

Key Research Applications

  1. Pharmaceutical Research:

    • Skin-lightening mechanisms
    • Melanin synthesis inhibition studies
    • Tyrosinase inhibition research
    • Safety and efficacy evaluations
  2. Cosmetic Development:

    • Skin brightening formulations
    • Anti-hyperpigmentation studies
    • Natural cosmetic ingredient research
    • Stability testing in various formulations
  3. Biochemical Studies:

    • Enzyme inhibition mechanisms
    • Cell culture investigations
    • Bioavailability studies
    • Structure-activity relationship analysis

Biological Properties

  • Natural tyrosinase inhibitor
  • Melanin synthesis regulation
  • Antioxidant activity
  • Non-cytotoxic at recommended concentrations
  • Superior stability compared to hydroquinone

Quality Assurance

  • Manufactured under GMP guidelines
  • Full Certificate of Analysis provided
  • Comprehensive analytical documentation
  • Batch-specific purity testing
  • Endotoxin and microbial testing are available

Research Areas

Ideal for studies in:

  • Dermatological research
  • Cosmetic science
  • Cell Biology
  • Pharmaceutical development
  • Natural product chemistry

Added Value Features

  • Research-grade purity
  • Full technical documentation
  • Method development support
  • Stability data available
  • Custom synthesis capabilities

Target Industries

  • Pharmaceutical R&D
  • Cosmetic development
  • Academic research
  • Biotechnology
  • Contract research organizations

Regulatory Information

  • Meets USP/EP specifications
  • Suitable for research and development
  • Available with full regulatory documentation
  • Compliant with international quality standards

For research and development purposes only. Not for human consumption or direct cosmetic application.

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Most Common Questions

For you to better choose the right compounds,  and so the scientific research can be carried out smoothly, here are some FAQs.

Delivery times vary based on order size, We deliver small quantities of compounds within 2 working days, ranging from one week for up to 500 compounds to about 6 weeks for orders exceeding 5,000 compounds.

While our focus is on natural compounds, we can provide information on natural product-like synthetic compounds if requested.

  • Yes, we can assist in selecting compounds that may be relevant to specific biological targets based on their structural characteristics and known activities.

Yes, we provide comprehensive analytical data and certificates of analysis for all our compounds.

Yes, we can re-supply active compounds in larger quantities and offer analogs for further testing if hits are discovered.

We offer a wide range of natural compounds including alkaloids, terpenoids, flavonoids, coumarins, peptides, glycosides, and nucleosides isolated from plants.

Our compounds undergo rigorous purification processes and are tested using advanced analytical methods such as NMR, mass spectroscopy, and in some cases, X-ray analysis to ensure >98% purity.

Yes, we offer custom isolation services for specific natural compounds based on client requirements.

We typically offer quantities ranging from 2 mg to 100 mg for screening purposes, with larger amounts available upon request.

We use various physicochemical analytical methods, including NMR (300-500 MHz) and mass spectroscopy, to confirm structures and stereochemistry.

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