Description

IUPAC Name: (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid;azane

InChI: InChI=1S/C42H62O16.H3N/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);1H3/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;/m0./s1

InChIKey: ILRKKHJEINIICQ-OOFFSTKBSA-N

Canonical SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C.N

Isomeric SMILES: C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O.N

Synonyms: Ammonium glycyrrhizate; AMMONIUM GLYCYRRHIZINATE; 53956-04-0; Glycamil; Monoammonium glycyrrhizinate; Glycyrram; Glycyrrhizic acid ammonium salt; Monoammonium glycyrrhizate; …

Botanical Source: Glycyrrhiza Radix Et Rhizoma

Product Overview

Ammonium glycyrrhizate is a bioactive triterpenoid saponin and the ammonium salt of glycyrrhizic acid, known for its anti-inflammatory, hepatoprotective, and sweetening properties. BIORLAB provides high-purity ammonium glycyrrhizate isolated through advanced purification techniques.

Technical Specifications

• Molecular Formula: C₄₂H₆₂O₁₆.H₃N
• Molecular Weight: 840 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Highly soluble in water, partially soluble in ethanol
• pH: 4.5-6.5 (2% aqueous solution)

Storage and Handling

• Store at 2-8°C in sealed containers
• Protect from light and moisture
• Stability: 3 years when properly stored
• Stock solution: Prepare in water
• Working solutions: Use appropriate buffers

Key Research Applications

Anti-inflammatory Research

• Cortisol-like activity studies
• NF-κB pathway investigation
• Pro-inflammatory cytokine modulation
• COX-2 expression studies

Hepatoprotective Studies

• Liver function research
• Hepatic enzyme modulation
• Oxidative stress protection
• Cell membrane stability

Pharmaceutical Applications

• Drug delivery systems
• Sweetening agent research
• Bioavailability enhancement
• Formulation studies

Quality Assurance

• HPLC purity analysis
• Structure verified by NMR
• Complete Certificate of Analysis
• Batch-specific documentation
• Meets USP/EP standards

Research Benefits

• High water solubility
• Excellent stability
• Comprehensive documentation
• Batch consistency
• Multiple research applications

Research Applications Highlights

1. Anti-inflammatory Mechanisms

   • Glucocorticoid-like effects
   • Cytokine regulation
   • Inflammatory mediators
   • Immune modulation

2. Hepatic Research

   • Liver protection
   • Enzyme regulation
   • Antioxidant effects
   • Cell membrane stability

3. Pharmaceutical Development

   • Excipient studies
   • Bioavailability research
   • Formulation development
   • Taste masking applications

Why Choose BIORLAB’s Ammonium Glycyrrhizate?

• Pharmaceutical grade purity
• Expert technical support
• Full analytical documentation
• Competitive Pricing
• Global shipping capability
• Custom synthesis options

Technical Support

• Method development assistance
• Analytical protocols
• Stability data
• Storage recommendations
• Application Guidance

For research use only. Not for human consumption or therapeutic use.