Description
2′-Hydroxygenistein, a natural flavonoid isolated from the roots of *Lupinus mutabilis*, possesses antifungal activity, with its dimerization significantly enhancing this effect. 2′-Hydroxygenistein also demonstrates greater antiproliferative effects in MCF-7 human breast cancer cells compared to **genistein**, indicating that 2′-hydroxylation of genistein can boost its antioxidant activity and cell cytotoxicity in MCF-7 human breast cancer cells.
IUPAC Name: 3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
InChI: InChI=1S/C15H10O6/c16-7-1-2-9(11(18)3-7)10-6-21-13-5-8(17)4-12(19)14(13)15(10)20/h1-6,16-19H
InChIKey: GSSOWCUOWLMMRJ-UHFFFAOYSA-N
SMILES: C1=CC(=C(C=C1O)O)C2=COC3=CC(=CC(=C3C2=O)O)O
Synonyms: 2′-Hydroxygenistein; 1156-78-1; 3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; 2′,4′,5,7-Tetrahydroxyisoflavone; CHEMBL6665; Isoflavone, 2′,4′,5,7-tetrahydroxy-; CHEBI:70031; …
Botanical Source: