Description
2-Hydroxy-3-methylanthraquinone, a derivative of anthraquinone, is extracted from the herbs of *Scutellaria barbata* D. Don. 2-Hydroxy-3-methylanthraquinone enhances apoptosis of THP-1 cells and U937 cells, partly through activation of Fas/FasL, DR4, TRAIL, and p-p38MAPK. 2-Hydroxy-3-methylanthraquinone induces apoptosis via caspase-8 and caspase-3 activation.
IUPAC Name: 2-hydroxy-3-methylanthracene-9,10-dione
InChI: InChI=1S/C15H10O3/c1-8-6-11-12(7-13(8)16)15(18)10-5-3-2-4-9(10)14(11)17/h2-7,16H,1H3
InChIKey: RNJHIYAJJKOFIO-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1O)C(=O)C3=CC=CC=C3C2=O
Synonyms: 2-Hydroxy-3-methylanthraquinone; 17241-40-6; 2-Hydroxy-3-methylanthracene-9,10-dione; DTXSID20447312; 2-Hydroxy-3-methylanthraquine; 2-Methyl-3-hydroxyanthraquinone; 3-Hydroxy-2-methylanthraquinone; 2-Hydroxy-3-methyl-9,10-anthracenedione; 2-?Hydroxy-?3-?methyl-9,?10-anthracenedione; SCHEMBL6051235; CHEMBL3896634; …
Botanical Source: