Description

IUPAC Name: (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol

InChI: InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1

InChIKey: LXBIFEVIBLOUGU-JGWLITMVSA-N

Canonical SMILES: C1C(C(C(C(N1)CO)O)O)O

Isomeric SMILES: C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O

Synonyms: 1-DEOXYNOJIRIMYCIN; 19130-96-2; DUVOGLUSTAT; deoxynojirimycin; Moranoline; (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol; Moranolin; 1 Deoxynojirimycin; …

Botanical Source: Mori Folium

Product Overview

High-purity 1-Deoxynojirimycin (DNJ, Moranoline), a natural glucose analog and potent α-glucosidase inhibitor isolated from mulberry leaves and Streptomyces cultures, manufactured to exceptional standards for diabetes and glycobiology research.

Technical Specifications

• Molecular Formula: C₆H₁₃NO₄
• Molecular Weight: 163.17 g/mol
• Purity: ≥98% (HPLC)
• Appearance: White crystalline powder
• Solubility: Highly soluble in water; soluble in methanol

Key Features & Benefits

• Natural iminosugar compound
• Potent glycosidase inhibitor
• Validated structure and activity
• Comprehensive Certificate of Analysis
• Full spectroscopic characterization

Research Applications

1. Diabetes Research

   • α-Glucosidase inhibition studies
   • Glucose metabolism research
   • Antihyperglycemic investigations
   • Insulin sensitivity studies

2. Glycobiology Studies

   • Glycoprotein processing
   • N-glycan synthesis research
   • Enzyme inhibition studies
   • Protein folding investigations

3. Therapeutic Development

   • Antidiabetic drug research
   • Lysosomal storage disease studies
   • Viral infection research
   • Obesity-related studies

Storage & Handling

• Store at -20°C
• Protect from moisture
• Hygroscopic nature requires careful handling
• Stock solution guidelines provided
• 24-month stability under recommended conditions

Quality Assurance

• GMP-compliant manufacturing
• Rigorous quality control
• Complete analytical documentation
• Traceable lot numbers
• Stability monitoring program

Research Support

BIORLAB provides:

• Technical consultation
• Analytical method support
• Stability data
• Custom synthesis options
• Application Guidance

Key Research Areas

1. Metabolic Disorders

   • Type 2 diabetes research
   • Obesity studies
   • Glucose homeostasis
   • Enzyme inhibition mechanisms

2. Glycoprotein Processing

   • ER quality control
   • Protein folding studies
   • N-glycan modifications
   • Cellular trafficking

3. Antiviral Research

   • Viral glycoprotein processing
   • Infection mechanism studies
   • Drug development screening

This premium-grade 1-Deoxynojirimycin is specifically designed for research institutions and pharmaceutical companies advancing therapeutic development and scientific research.

For research and development purposes only. Not for human consumption or clinical use.

[Contact BIORLAB’s technical support team for detailed specifications and custom requirements]