Description
IUPAC Name: (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
InChI: InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey: KQJSQWZMSAGSHN-JJWQIEBTSA-N
Canonical SMILES: CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
Isomeric SMILES: CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O
Synonyms: celastrol; 34157-83-0; Tripterin; Tripterine; (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid; NSC70931; (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid; CHEBI:63959; …
Botanical Source: Tripterygium wilfordii Hook.f.
Product Overview
BIORLAB provides high-purity Celastrol (≥98%), a potent bioactive compound isolated from Tripterygium wilfordii. Our pharmaceutical-grade celastrol supports cutting-edge research in anti-inflammatory, anti-obesity, and neurodegenerative studies.
Technical Specifications
- Molecular Formula: C₂₉H₃₈O₄
- Molecular Weight: 450.6 g/mol
- Appearance: Red crystalline powder
- Purity: ≥98% (HPLC)
- Solubility: Soluble in DMSO, ethanol
- Storage: -20°C
- Form: Crystalline powder
Quality Assurance
- Full spectroscopic characterization
- Comprehensive Certificate of Analysis
- Batch-specific HPLC profiles
- Stability testing data
- Research-grade documentation
Storage & Handling
- Store at -20°C
- Protect from light and moisture
- Available in research quantities
- Stability data provided
- Special handling protocols available
Research Applications
Anti-inflammatory Research
- NF-κB pathway studies
- Cytokine modulation
- Inflammatory mediator research
- Autoimmune disease studies
Metabolic Research
- Leptin sensitization studies
- Anti-obesity investigations
- Energy homeostasis research
- Metabolic regulation studies
Key Research Areas
-
Neurodegenerative Studies
- Protein aggregation
- Heat shock response
- Neuroprotection
- Stress response pathways
-
Cancer Research
- Anti-proliferative mechanisms
- Apoptosis induction
- Angiogenesis inhibition
- Drug resistance studies
Product Features & Benefits
- Highest available purity
- Batch-to-batch consistency
- Comprehensive documentation
- Technical support available
- Custom packaging options
Target Applications
- Pharmaceutical R&D laboratories
- Neuroscience research centers
- Cancer research facilities
- Academic research institutions
Research Significance
-
Therapeutic Potential
- Anti-inflammatory effects
- Obesity management
- Neuroprotection
- Cancer treatment
-
Biological Activities
- HSF1 activation
- NF-κB inhibition
- Proteasome modulation
- Leptin sensitization
Technical Support Features
- Method development assistance
- Analytical testing guidance
- Stability data available
- Research protocol support
- Documentation assistance
For detailed technical information, bulk quantities, or custom requirements, contact BIORLAB’s scientific team.
Note: This product is intended for laboratory research purposes only. Not for human consumption or therapeutic use without proper approval.