Description
High-purity Robinin, a flavonoid glycoside isolated from Astragalus falcatus Lem, demonstrating significant anti-inflammatory and renal protective properties.
Technical Specifications
- Molecular Formula: C₃₃H₄₀O₁₉
- Molecular Weight: 740.7 g/mol
- Purity: ≥98% (HPLC)
- Appearance: White to off-white powder
IUPAC Name: 5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
InChI: InChI=1S/C33H40O19/c1-10-19(36)23(40)26(43)31(47-10)46-9-17-21(38)25(42)28(45)33(51-17)52-30-22(39)18-15(35)7-14(49-32-27(44)24(41)20(37)11(2)48-32)8-16(18)50-29(30)12-3-5-13(34)6-4-12/h3-8,10-11,17,19-21,23-28,31-38,40-45H,9H2,1-2H3/t10-,11-,17+,19-,20-,21-,23+,24+,25-,26+,27+,28+,31+,32-,33-/m0/s1
InChIKey: PEFASEPMJYRQBW-HKWQTAEVSA-N
Canonical SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OC5C(C(C(C(O5)C)O)O)O)C6=CC=C(C=C6)O)O)O)O)O)O)O
Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)C6=CC=C(C=C6)O)O)O)O)O)O)O
Synonyms: Robinin; 301-19-9; Kaempferol-3-O-gal-rham-7-O-rham; EINECS 206-113-3; NSC 9222; Kaempferol-3-O-robinoside-7-O-rhamnoside; 75RT1VGM60; 3-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl)oxy)-7-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; …
Botanical Source: Dendranthema indicum
Key Features & Benefits
- Natural flavonoid glycoside
- Anti-inflammatory properties
- Renal protective effects
- Used in chronic renal failure therapy
- Original drug “Flaronin” component
Research Applications
-
Pharmaceutical Development
- Liposomal formulations
- Nanoparticle development
- Drug delivery systems
- Bioavailability studies
-
Clinical Research
- Renal failure therapy
- Anti-inflammatory studies
- Bioactivity assessment
- Safety evaluations
Storage & Handling
- Store at -20°C
- Protect from light and moisture
- Avoid repeated freeze-thaw cycles
- Monitor stability
- Follow safety guidelines
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Current Applications
-
Therapeutic Use
- Chronic renal failure treatment
- Anti-inflammatory therapy
- Diuretic applications
- Renal function improvement
-
Drug Development
- Novel delivery systems
- Formulation optimization
- Bioavailability enhancement
- Safety assessment
Technical Support
- Method validation
- Analytical standards
- Formulation guidance
- Stability data
- Application support
For research and development purposes only. Not for human consumption or clinical use.