Description
IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
InChI: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChIKey: KZNIFHPLKGYRTM-UHFFFAOYSA-N
Canonical SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Isomeric SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Synonyms: apigenin; 520-36-5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Versulin; Apigenol; Chamomile; 4′,5,7-Trihydroxyflavone; Spigenin; …
Botanical Source: Apium graveolens L.
Apigenin (4′,5,7-trihydroxyflavone) is a naturally occurring flavonoid compound found abundantly in common fruits and vegetables, particularly in parsley, celery, and chamomile tea. At BIORLAB, we offer high-purity apigenin (≥98%) isolated through advanced separation techniques for pharmaceutical research and development applications.
Chemical Properties
– Molecular Formula: C₁₅H₁₀O₅
– Molecular Weight: 270.24 g/mol
– CAS Number: 520-36-5
– Appearance: Yellow crystalline powder
– Solubility: Soluble in DMSO and hot ethanol
Key Applications in Pharmaceutical Research
Anti-inflammatory Properties
Apigenin demonstrates significant anti-inflammatory activity through inhibition of pro-inflammatory cytokines and NF-κB signaling pathways, making it valuable for developing anti-inflammatory therapeutics.
Cancer Research Applications
– Exhibits potential anti-cancer properties through multiple mechanisms
– Induces cell cycle arrest and apoptosis in various cancer cell lines
– Shows promise in combination therapy studies
– Demonstrates selective cytotoxicity towards cancer cells
Neuroprotective Research
Research indicates apigenin’s potential in:
– Reducing oxidative stress in neuronal cells
– Supporting cognitive function
– Protecting against neurodegenerative conditions
Quality Assurance
– High-purity grade (≥98%) suitable for research applications
– Comprehensive Certificate of Analysis provided
– Rigorous quality control testing
– Full spectral data available upon request
Storage and Handling
– Store at -20°C
– Protect from light and moisture
– Stable for 2 years when properly stored
– Available in various pack sizes
Research Support
Our technical support team provides:
– Detailed product documentation
– Application Guidance
– Custom synthesis solutions
– Method development assistance
Contact BIORLAB for premium quality apigenin and expert technical support for your pharmaceutical research needs.