Description

IUPAC Name: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one

InChI: InChI=1S/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8,18-19H,1-2H3

InChIKey: ROCUOVBWAWAQFD-UHFFFAOYSA-N

Canonical SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O

Isomeric SMILES: COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O

Synonyms: Velutin; 25739-41-7; Flavoyadorigenin B; 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one; UNII-CT1Q4E0I0W; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one; CT1Q4E0I0W; Luteolin 7,3′-dimethyl ether; …

Botanical Source: Callicarpa formosana Rolfe

Velutin (CAS: 25739-41-7) | Premium Flavonoid Research Compound

Technical Specifications

• Molecular Formula: C₁₇H₁₄O₆
• Molecular Weight: 314.29 g/mol
• Purity: ≥98%
• Appearance: Yellow powder
• Source: The leaves of Vernonia flexuosa
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone

Research Applications

Biological Activities

1. Anti-inflammatory Properties

   • TNF-α and IL-6 production inhibition
   • NF-κB activation suppression
   • p38 and JNK phosphorylation inhibition
   • Proinflammatory cytokine regulation

2. Additional Properties

   • Anti-allergic agent
   • Melanin synthesis inhibitor
   • Antibacterial agent
   • Antioxidant activity

Key Research Areas

Primary Functions

• Anti-inflammatory research
• Plant metabolite studies
• Melanin synthesis inhibition
• Antibacterial investigations

Storage Requirements

• Store according to manufacturer specifications
• Protect from light and moisture
• Special handling protocols required
• Stability data available

Research Significance

Anti-inflammatory Mechanism

• Effectively inhibits proinflammatory cytokines
• Blocks NF-κB activation
• Inhibits MAPK pathway
• Controls HIF-1α activity

HIF-1α Activity Control

• Modulates NF-κB pathway
• Potential therapeutic use in periodontitis
• Prevention of bone loss
• Osteoclastogenesis regulation

Quality Control

• Full spectroscopic analysis
• HPLC purity verification
• Structure confirmation
• Batch-specific documentation

For detailed technical information, bulk quantities, or custom requirements, contact our scientific team.

Note: This product is intended for laboratory research purposes only.