Description
High-purity Cryptotanshinone, a bioactive diterpene quinone isolated from Salvia miltiorrhiza (Danshen), demonstrating significant anti-cancer, anti-inflammatory, and cardiovascular protective properties.
Technical Specifications
- Molecular Formula: C₁₉H₂₀O₃
- Molecular Weight: 296.4 g/mol
- Purity: ≥98% (HPLC)
- Appearance: Orange-red crystalline powder
- Solubility: Soluble in DMSO, ethanol; poorly soluble in water
IUPAC Name: (1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-10,11-dione
InChI: InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
InChIKey: GVKKJJOMQCNPGB-JTQLQIEISA-N
Canonical SMILES: CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
Isomeric SMILES: C[C@H]1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
Synonyms: Cryptotanshinone; 35825-57-1; Tanshinone c; Cryptotanshinon; (R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione; (15R)-cryptotanshinone; C19H20O3; UNII-5E9SXT166N; …
Botanical Source: Salviae Miltiorrhizae Radix et Rhizoma
Key Features & Benefits
- Natural diterpenoid quinone
- STAT3 inhibition activity
- Anti-tumor properties
- Comprehensive Certificate of Analysis
- Full spectroscopic characterization
- Complete traceability
Research Applications
-
Cancer Research
- STAT3 pathway inhibition
- Anti-proliferation studies
- Apoptosis induction
- Drug resistance research
-
Cardiovascular Studies
- Cardioprotective mechanisms
- Atherosclerosis research
- Vascular function studies
- Anti-thrombotic investigations
-
Anti-inflammatory Research
- NF-κB pathway modulation
- Cytokine regulation
- Inflammatory mediators
- Immune response studies
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Package Sizes
- 5mg
- 10mg
- 25mg
- 100mg
- Bulk quantities available
Key Research Areas
-
Molecular Mechanisms
- STAT3 signaling
- Cell cycle regulation
- Apoptotic pathways
- Anti-angiogenic effects
-
Disease Applications
- Cancer therapy
- Cardiovascular protection
- Inflammatory conditions
- Metabolic disorders
Biological Activities
- STAT3 inhibition (IC50 documented)
- Anti-proliferative effects
- Anti-inflammatory properties
- Cardiovascular protection
This premium-grade Cryptotanshinone is designed for research institutions and pharmaceutical companies advancing therapeutic development.
For research and development purposes only. Not for human consumption or clinical use.