Description
Mahanine, a carbazole alkaloid found in the edible parts of Micromelum minutum, Murraya koenigii, and related species, is a DNA minor groove binding agent known for its potent anticancer activity. Mahanine also demonstrates antileishmanial properties, making it a potential candidate for research in the treatment of Leishmania infections.
IUPAC Name: (3R)-3,5-dimethyl-3-(4-methylpent-3-enyl)-11H-pyrano[3,2-a]carbazol-9-ol
InChI: InChI=1S/C23H25NO2/c1-14(2)6-5-10-23(4)11-9-18-21-19(12-15(3)22(18)26-23)17-8-7-16(25)13-20(17)24-21/h6-9,11-13,24-25H,5,10H2,1-4H3/t23-/m1/s1
InChIKey: DWMBXHWBPZZCTN-HSZRJFAPSA-N
SMILES: CC1=CC2=C(C3=C1O[C@](C=C3)(C)CCC=C(C)C)NC4=C2C=CC(=C4)O
Synonyms: Mahanine; 28360-49-8; (-)-Mahanin; (R)-3,5-Dimethyl-3-(4-methylpent-3-en-1-yl)-3,11-dihydropyrano[3,2-a]carbazol-9-ol; (-)-Mahanine; (3R)-3,5-dimethyl-3-(4-methylpent-3-enyl)-11H-pyrano[3,2-a]carbazol-9-ol; Mahanine, (-)-; KBJ2W7E9BH; …
Botanical Source: